Magnetic resonance imaging of sellar and juxtasellar abnormalities in the paediatric population: an imaging review

Insights Into Imaging
Rachel ShieldsSteven Meyers

Abstract

The sellar and juxtasellar regions in the paediatric population are complex both anatomically and pathologically, with magnetic resonance imaging (MRI) being the "gold standard" imaging modality due to the high contrast of detail. Assessment requires a detailed understanding of the anatomy, embryology, pathophysiology and normal signal characteristics of the pituitary gland and surrounding structures in order to appropriately characterise abnormalities. This article aims to provide an overview of the imaging characteristics of developmental/congenital and acquired disease processes which affect the sellar and juxtasellar region in the paediatric population. Main Messages • The sellar region is anatomically complex and covers a wide pathology spectrum. • MRI is the key imaging modality to assess sellar and juxtasellar pathology. • Numerous developmental anomalies may not be discovered until adulthood. • Knowledge of pathology alerts and guides the clinician towards appropriate management.

References

May 1, 1989·Journal of Computer Assisted Tomography·I FujisawaS Noma
Aug 1, 1985·Journal of Neurosurgery·M T JenningsF Hochberg
Jan 1, 1988·Neuroradiology·Y NemotoY Onoyama
Nov 1, 1987·Radiology·W KucharczykT H Newton
Mar 1, 1987·Journal of Computer Assisted Tomography·I FujisawaK Torizuka
Jan 1, 1981·Journal of Neuropathology and Experimental Neurology·S S Rengachary, I Watanabe
May 1, 1995·Journal of Child Neurology·M C Chamberlain
Feb 1, 1995·Neurosurgery·T Mindermann, C B Wilson
Feb 1, 1994·Journal of Neurosurgery·M D PartingtonB W Scheithauer
Jan 26, 1999·Pediatric Neurosurgery·J U Choi, D S Kim
Aug 30, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S J CotterillA W Craft
Sep 7, 2000·Australasian Radiology·M R Sage, P C Blumbergs
Oct 6, 2000·The New England Journal of Medicine·M MaghnieM Aricò
Nov 15, 2000·Surgical Neurology·A JabreR Samaraweera
Apr 11, 2001·Annals of Diagnostic Pathology·M WuL B Kahn
Aug 31, 2002·Endocrine Reviews·Laurie E Cohen, Sally Radovick
Dec 17, 2002·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Gökhan KurtM Kemali Baykaner
Aug 28, 2003·European Radiology·A BernaertsA M De Schepper
Jan 20, 2004·Brain & Development·Pasquale Di PietroMaria Paola Fondelli
Mar 26, 2004·Tropical Medicine & International Health : TM & IH·F van den BosP R Donald
Jan 27, 2005·Radiology·Christopher P VittoreLaura S Martin
Jan 29, 2005·European Radiology·J Ruscalleda
Mar 8, 2005·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·P PandeyA K Mahapatra
Apr 6, 2005·American Journal of Medical Genetics. Part a·Anne SlavotinekEric Huang
Jun 2, 2005·Neuroimaging Clinics of North America·Mark Pisaneschi, Geetanjali Kapoor
Dec 15, 2005·The British Journal of Radiology·Z K ShahT W H Shek
Mar 10, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Tracy Batchelor, Jay S Loeffler
Jun 21, 2006·Topics in Magnetic Resonance Imaging : TMRI·M Vittoria Spampinato, Mauricio Castillo
Jun 21, 2006·Topics in Magnetic Resonance Imaging : TMRI·J Keith Smith
Nov 23, 2006·Radiology·Luisa F CervantesL Santiago Medina
Feb 22, 2007·AJR. American Journal of Roentgenology·Bronwyn E HamiltonAnne G Osborn
May 18, 2007·Neuro-Chirurgie·G LenaD Scavarda
Jul 10, 2007·Acta Neuropathologica·David N LouisPaul Kleihues
Jul 11, 2007·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Sahar N SaleemDonald H Lee
Jan 5, 2008·Journal of Neurosurgery·Mandy J BinningWilliam T Couldwell
Aug 15, 2008·AJNR. American Journal of Neuroradiology·L L LinscottC L Sutton
Mar 25, 2009·Pediatric Neurosurgery·Nicola AcciarriFabio Calbucci
Dec 1, 2009·Endocrinology and Metabolism Clinics of North America·Bradley N Delman
Jul 24, 2010·AJNR. American Journal of Neuroradiology·Y NakataK Ohtomo
Jul 27, 2010·Journal of Computer Assisted Tomography·Chhavi KaushikEdgardo J Angtuaco

❮ Previous
Next ❯

Citations

Jan 31, 2016·Journal of Magnetic Resonance Imaging : JMRI·Sandra M MeyersAnthony L Traboulsee
Jul 29, 2019·Pediatric Radiology·Eman S MahdiMatthew T Whitehead

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Seminars in Neurology
Joshua W Lucas, Gabriel Zada
Clinical Neurology and Neurosurgery
Janine Rennert, Arnd Doerfler
Journal of Neuroradiology. Journal De Neuroradiologie
G CrouzetJ F Le Bas
© 2021 Meta ULC. All rights reserved