PMID: 15228185Jul 2, 2004Paper

Magnetic resonance imaging of the knee: a tool for prediction of joint damage in early rheumatoid arthritis?

Scandinavian Journal of Rheumatology
Kristina ForslindB Svensson

Abstract

To evaluate the usefulness of magnetic resonance imaging (MRI) in predicting destructive rheumatoid arthritis (RA) in the knee joint, and to compare this method with clinical examination and conventional radiography (CR). Clinical evaluations of the knee joint, followed by MRI and CR examinations were performed in 30 patients with early RA. The MRI examination included evaluation of inflammation using a synovitis score and evaluation of destruction with an erosion score. The first examinations were performed within 14 months from disease onset. Twenty-eight patients were re-examined after 1 year, and 23 patients after 3 years. 'Disease activity score' (DAS), using a 28 joints score (DAS28); health assessment questionnaire (HAQ); rheumatoid factor (RF); and C-reactive protein (CRP) were also analysed. At baseline, MRI found synovitis in 29 patients, of whom 18 also had clinical synovitis. At baseline five patients had 17 MRI erosions, whereas on CR two patients had one erosion each. After 1 year 17 of 35 and after 3 years 28 of 55 MRI erosions were detected also on CR. In only one case CR showed an erosion that was not visible on MRI. The MRI synovitis score (reflecting the extent of the synovitis) at baseline correlated signifi...Continue Reading

References

Jan 1, 1992·Radiology·C M Hervé-SommaD P Lallemand
Sep 1, 1990·Radiology·S Kursunoglu-BrahmeC Fix
Jan 1, 1982·Scandinavian Journal of Rheumatology·S Jalava, K Reunanen
Feb 1, 1980·Arthritis and Rheumatism·J F FriesH R Holman
Feb 1, 1997·British Journal of Rheumatology·J R Kirwan
May 10, 2003·Scandinavian Journal of Rheumatology·Mikkel Ostergaard, Marcin Szkudlarek

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Citations

Sep 19, 2006·Proceedings of the National Academy of Sciences of the United States of America·Satoshi KanazawaB Matija Peterlin
Nov 6, 2007·Radiologic Clinics of North America·Matthew A FrickMark Adkins
May 15, 2007·Magnetic Resonance Imaging Clinics of North America·Matthew A FrickMark Adkins
Apr 20, 2005·Current Opinion in Rheumatology·Helen I Keen, Paul Emery

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