Magnetic resonance imaging spectrum of intracranial tubercular lesions: one disease, many faces

Polish journal of radiology
Garvit Devmohan KhatriGaurav Saigal

Abstract

Tuberculosis is a devastating disease and has shown resurgence in recent years with the advent of acquired immunodeficiency syndrome. Central nervous system involvement is the most devastating form of the disease, comprising 10% of all tuberculosis cases. The causative organism, Mycobacterium tuberculosis, incites a granulomatous inflammatory response in the brain, the effects of which can be appreciated on magnetic resonance imaging (MRI), which can thus be used for diagnosis of the same. Neurotuberculosis can present in various patterns, which can be identified on MRI. The meningeal forms include leptomeningitis and pachymeningitis. Parenchymal forms of neurotuberculosis include tuberculoma in its various stages, tubercular cerebritis and abscess, tubercular rhombencephalitis, and tubercular encephalopathy. Each pattern has characteristic MRI appearances and differential diagnoses on imaging. Complications of neurotuberculosis, usually of tubercular meningitis, include hydrocephalus, vasculitis, and infarcts as well as cranial nerve palsies. Various MRI sequences besides the conventional ones can provide additional insight into the disease, help in quantifying the disease load, and help in differentiation of neurotuberculosis...Continue Reading

Citations

Jan 12, 2020·Neuroradiology·Joseph C J BotFrederik Barkhof
Jan 6, 2021·Acta neurologica Belgica·Ajith CherianK P Divya
Feb 4, 2021·Journal of Neurosciences in Rural Practice·Paromita DuttaManisha Mishra
Apr 16, 2021·Radiologia brasileira·Heloisa Sisconeto BisinottoFabiano Reis
Jun 4, 2021·Journal of the Neurological Sciences·Rajeev RanjanVivek Lal
Oct 10, 2020·Current Problems in Diagnostic Radiology·Houman SotoudehAparna Singhal

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