Magnetic resonance spectroscopy in psychiatry: basic principles and applications

British Medical Bulletin
S Frangou, S C Williams

Abstract

In vivo magnetic resonance spectroscopy (MRS) is a safe and non-invasive tool which can be used to study aspects of brain chemistry and metabolism. Although a relatively recent technique in the field of psychiatric research, it has already been used in the study of anxiety and affective disorders, dementia, schizophrenia, and neurodevelopmental disorders. This review outlines the basic principles of MRS and summarises the research findings in psychiatric disorders. Although mostly preliminary, these findings highlight the capacity of MRS to detect subtle neurobiological abnormalities in mental disorders. They also suggest a future role for MRS in differential diagnosis and monitoring illness progression. Initial MRS studies have also focused on the metabolic effects of psychiatric treatments and could provide information about their relationship to clinical variables.

Citations

Feb 24, 2001·The Australian and New Zealand Journal of Psychiatry·A L VanceC Pantelis
Jun 5, 2012·The American Journal of Clinical Hypnosis·Catherine G Fine
Jan 5, 2011·Depression Research and Treatment·Douglas G KondoPerry F Renshaw
Aug 19, 2015·Journal of the American Psychiatric Nurses Association·Tracy HellemPerry F Renshaw
Feb 18, 2011·Psychological Reports·Fay Griva, Fotios Anagnostopoulos

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