Magnetically Controlled Devices Parallel to the Spine in Children with Spinal Muscular Atrophy

JB & JS Open Access
Heiko M LorenzA K Hell

Abstract

Children with severe spinal deformity frequently are managed with growth-friendly implants. After initial surgery, externally controlled magnetic rods allow spinal deformity correction during growth without further surgical intervention. The ability to lengthen the spine without additional surgical procedures is especially beneficial in high-risk children, such as those with spinal muscular atrophy (SMA). The purpose of the present study was to assess the level of control of spinal deformity in a homogeneous group of patients with SMA who were managed with magnetically controlled implants for 2 years. This prospective, nonrandomized study included 21 non-ambulatory children with type-II SMA and progressive scoliosis who were managed bilaterally with a magnetically controlled implant that was inserted parallel to the spine with use of rib-to-pelvis hook fixation. Radiographic measurements of scoliotic curves, kyphosis, lordosis, pelvic obliquity, and spinal length were performed before and after implantation of the magnetically controlled device and during external lengthening. The mean duration of follow-up was 2 years. The mean main curve of patients without prior vertical expandable prosthetic titanium rib (VEPTR) treatment d...Continue Reading

References

Feb 3, 2007·The Journal of Bone and Joint Surgery. American Volume·Robert M Campbell, Melvin D Smith
Apr 7, 2007·Journal of Pediatric Orthopedics·George H ThompsonRobert M Campbell
Dec 31, 2009·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Carol-Claudius HaslerFritz Hefti
Oct 5, 2010·The Journal of Bone and Joint Surgery. American Volume·Shay BessDavid L Skaggs
Feb 22, 2011·Spine·Wudbhav N SankarBehrooz A Akbarnia
Jan 12, 2013·The Bone & Joint Journal·Z DannawiH Noordeen
Apr 23, 2013·Paediatric Anaesthesia·Gunilla Islander
Sep 3, 2013·Journal of Pediatric Orthopedics·David L SkaggsUNKNOWN Scoliosis Research Society Growing Spine Study Committee
Oct 23, 2013·World Journal of Orthopedics·Federico Canavese, Alain Dimeglio
Jan 15, 2014·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·B A HickeyS Ahuja
May 16, 2015·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Christian PlaassDaniel Studer
Jan 4, 2017·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Julie LebonJérôme Sales De Gauzy

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Citations

Aug 19, 2020·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Ishaan SwarupPatrick J Cahill
Jun 19, 2019·Operative Orthopädie und Traumatologie·H M LorenzA-K Hell
Dec 3, 2020·Cancers·Anna K HellKonstantinos Tsaknakis
Feb 24, 2021·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Sebastian LipprossAnna K Hell
Jul 8, 2021·Der Orthopäde·T-L Vu-HanM Pumberger
Dec 9, 2021·Médecine sciences : M/S·Étienne Saudeau

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