Magnetoencephalographic study of rhythmic mid-temporal discharges in non-epileptic and epileptic patients

Seizure : the Journal of the British Epilepsy Association
Y-Y LinL-T Ho

Abstract

To evaluate the source location and clinical significance of rhythmic mid-temporal theta discharges (RMTD) by MEG in non-epileptic and epileptic patients, we conducted simultaneous MEG and EEG recordings with a whole-scalp 306-channel neuromagnetometer in three patients: one with right temporal lobe epilepsy (TLE), one with right frontal lobe epilepsy (FLE), and one with tension headache. We visually detected the RMTD activity and interictal spikes, and then localised their generators by MEG source modelling. We repeated MEG measurement 3 months after right anterior temporal lobectomy (ATL) in the TLE patient; 3 months after anticonvulsant medication in the FLE patient. In epileptic patients, RMTD activities were found during drowsiness over the left temporal channels of both MEG and EEG recordings, and their generators were localised to the left posterior inferior temporal region. In the patient with tension headache, RMTD was localised in the right inferior temporal area. When the epileptic patients became seizure free with disappearance of epileptic spikes, RMTD was still found over the left temporal channels. Besides, some bursts of RMTD appeared also in the right temporal channels in our TLE patient after ATL. Our results ...Continue Reading

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Citations

Sep 12, 2003·Seizure : the Journal of the British Epilepsy Association·Yung-Yang LinRiitta Hari
Nov 15, 2011·Brain Topography·Andrew C N ChenFernando L Lopes da Silva
Oct 27, 2009·Neurologic Clinics·Lina Nashef, Philippe Ryvlin
Dec 21, 2006·Seizure : the Journal of the British Epilepsy Association·M C G VlooswijkA P Aldenkamp
Jul 6, 2019·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Joon Y Kang, Gregory L Krauss
Nov 10, 2020·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Stefan RamppRichard C Burgess

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