Magnopyramidal neurons in the anterior motor speech region. Dendritic features and interhemispheric comparisons

Archives of Neurology
T L Hayes, D A Lewis

Abstract

To test the hypothesis that the larger somal size of layer III magnopyramidal neurons in left than in right Brodmann area 45 is associated with greater measures of dendritic arborization in the left hemisphere neurons. A case series involving postmortem human brain specimens was used to compare dendritic parameters of Golgi-impregnated layer III pyramidal neurons in Brodmann area 45 in the left and right hemispheres. A convenience sample consisting of 9 subjects with no known neurologic or psychiatric disorders was obtained at autopsy. Dendritic parameters of the 10 largest Golgi-impregnated layer III pyramidal neurons were measured in each hemisphere of each brain using a eutectic neuron tracing system. The measures examined were somal size, neuron depth, mean segment length, number of branch points, maximal branch order, combined dendritic diameter, total dendritic length, horizontal extent of the dendritic field, and spine density. The Golgi-impregnated slides were also compared with Nissl-stained slides from adjacent blocks to determine the laminar location of the sampled neurons. Although the mean somal size was greater in the left than in the right hemisphere, none of the dendritic parameters examined was larger for the l...Continue Reading

Citations

Sep 30, 2010·PLoS Biology·Katrin AmuntsKarl Zilles
Nov 1, 2007·Clinical Linguistics & Phonetics·Milos Judas, Maja Cepanec
Jan 22, 2009·Brain and Language·Simon S KellerNeil Roberts
Sep 10, 2008·Brain and Cognition·Theodore RabinowiczGabrielle M de Courten-Myers
Aug 6, 2003·Trends in Neurosciences·Jeffrey Hutsler, Ralf A W Galuske
Aug 12, 1999·The Journal of Comparative Neurology·K AmuntsK Zilles
Sep 7, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·David A Lewis, Guillermo González-Burgos
Jul 10, 2008·The Journal of Comparative Neurology·Natalie M SchenkerKaterina Semendeferi
Sep 8, 2001·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J MazziottaB Mazoyer
May 31, 2007·The Journal of Comparative Neurology·Chet C SherwoodWilliam D Hopkins
Apr 13, 2015·Medical & Biological Engineering & Computing·Seppo P Ahlfors, Christopher Wreh
Jan 22, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Qingfei LuoJia-Hong Gao
Aug 28, 2001·Journal of the American Medical Informatics Association : JAMIA·J MazziottaB Mazoyer
Dec 20, 2003·Annals of the New York Academy of Sciences·David A LewisRobert A Sweet

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