PMID: 7033110Nov 1, 1981Paper

Maintenance of adult hamster pancreas cells on fibroblastic cells

In Vitro
L E MalickR Langenbach

Abstract

The maintenance of primary cultures of adult hamster pancreatic cells on layers of irradiated C3H/10T1/2 cells was studied. Various types of pancreatic cells, acinar, islet and ductular cells could be identified in the cultures by light and electron microscopy. Morphologically the various pancreatic cells retained many differentiated characteristics of their respective in vivo cells types. Insulin production was maintained at near Day 1 levels for the 16 d in culture for which it was measured. Colonies of epithelial cells continued to grow during a 20 d culture period. It is believed that this procedure for maintaining functional and growing pancreas cells in culture may be a useful in vitro model for studying the initiation of pancreatic carcinogenesis.

References

Oct 1, 1979·In Vitro·G MichalopoulosC Biles
Jun 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·R LangenbachE Huberman
Jan 1, 1979·Annual Review of Biochemistry·G Carpenter, S Cohen
Mar 1, 1977·Journal of the National Cancer Institute·R T JonesB F Trump
Oct 1, 1975·Journal of the National Cancer Institute·J DissinP D Webster
Nov 15, 1975·International Journal of Cancer. Journal International Du Cancer·R J ElkortP J Mozden
Jan 1, 1973·Endocrinology·W L ChickJ M Woodruff
Oct 1, 1965·The Journal of Clinical Endocrinology and Metabolism·V HerbertS J Bleicher
Jul 25, 1958·The Journal of Biophysical and Biochemical Cytology·M L WATSON

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Citations

Apr 1, 1983·In Vitro·J H ResauR T Jones
Jan 1, 1985·In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association·K JainM C Archer
May 1, 1986·Cell Differentiation·D MasquelierC Remacle

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