Maintenance of hydrostatic pressure gradients in the membranous labyrinth

Archives of Oto-rhino-laryngology
A Böhmer, J C Andrews

Abstract

In normal guinea pig ears, hydrostatic perilymphatic pressure is equal to endolymphatic pressure. Alterations of perilymphatic pressure induced, for example, by laceration of the round window membrane are transmitted immediately to the endolymphatic compartment, probably via Reissner's membrane. In guinea pigs with experimental endolymphatic hydrops, however, pressure gradients between the endolymph and perilymph remained preserved after rupture of the round window membrane. This is considered as further evidence that after long-standing distention of Reissner's membrane the membranous labyrinth loses its ability to equalize endolymphatic and perilymphatic pressure.

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Citations

Oct 16, 2009·Naunyn-Schmiedeberg's Archives of Pharmacology·Thorsten HaaslerAndreas Lückhoff
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Jun 14, 2013·Journal of Glaucoma·Carol A Silverman, Christopher J Linstrom
Jan 3, 2021·Journal of Vestibular Research : Equilibrium & Orientation·Idir Djennaoui, Paul Avan

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