PMID: 7032222May 1, 1981Paper

Maintenance of therapeutic effects of total sleep deprivation by limitation of subsequent sleep. A pilot study

Acta Psychiatrica Scandinavica
A L van Bemmel, R H van den Hoofdakker

Abstract

In a previous study it was shown that in endogenous depression repeated sleep deprivation (SD) during clomipramine treatment resulted in rapid improvement after each SD. However, except after the first night, relapses were observed after all sleep nights following SD (the "recovery nights"). The present pilot study had a therapeutic aim, namely to prevent these relapses. We were interested in whether limitation of sleep during the recovery nights might prevent these relapses and whether different amounts of sleep would have different effects on the course of mood after recovery sleep. Ten endogenously depressed patients were treated with clomipramine and with three SD's. Five patients slept for approximately 2 h, and the other five for about 5 h during the second and third recovery nights. On average, no relapse was shown by these patients and, in fact, there was some additional improvement after these nights, in contrast to the findings in the previous study, where patients were allowed unlimited sleep.

References

Jul 6, 1978·Archiv für Psychiatrie und Nervenkrankheiten·C Buddeberg, A Dittrich
Sep 1, 1975·Archives of General Psychiatry·W van den Burg, R H van den Hoofdakker
Feb 1, 1976·Acta Psychiatrica Scandinavica·B Pflug
May 1, 1976·Archives of General Psychiatry·R M PostF K Goodwin

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Citations

Jun 1, 1991·Biological Psychiatry·H Kuhs, R Tölle
Jan 1, 1982·Journal of Psychiatric Research·S Elsenga, R H van den Hoofdakker
Jan 1, 1990·Journal of Psychiatric Research·S ElsengaR H Van den Hoofdakker
Jan 1, 1987·Journal of Affective Disorders·E SouêtreG Darcourt
Jan 1, 1983·Progress in Neuro-psychopharmacology & Biological Psychiatry·J C Gillin
Jan 1, 1990·Progress in Neuro-psychopharmacology & Biological Psychiatry·H GiedkeH T Haffner
Jan 1, 1993·Progress in Neuro-psychopharmacology & Biological Psychiatry·R C Shelton, P T Loosen
Jun 1, 1997·Journal of Psychosomatic Research·A L van Bemmel
Aug 4, 2011·Neuropsychobiology·Francesco Benedetti, Cristina Colombo
Aug 21, 2013·Current Psychiatry Reports·Wallace C Duncan, Carlos A Zarate
Aug 1, 1994·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Z LelkesG Benedek
Jan 1, 1987·Journal of Psychiatric Research·S Elsenga, R H Van den Hoofdakker
Feb 1, 1988·Acta Psychiatrica Scandinavica·D A SackT A Wehr
Jan 1, 1988·Acta Psychiatrica Scandinavica. Supplementum·R H Van den Hoofdakker, D G Beersma
Sep 1, 1988·Biological Psychiatry·S Elsenga, R H Van den Hoofdakker
Jan 1, 1994·Journal of Biological Rhythms·R H Van den Hoofdakker

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