Maintenance Therapies for Hodgkin and Non-Hodgkin Lymphomas After Autologous Transplantation: A Consensus Project of ASBMT, CIBMTR, and the Lymphoma Working Party of EBMT

JAMA Oncology
Abraham S KanateM Hamadani

Abstract

Maintenance therapies are often considered as a therapeutic strategy in patients with lymphoma following autologous hematopoietic cell transplantation (auto-HCT) to mitigate the risk of disease relapse. With an evolving therapeutic landscape, where novel drugs are moving earlier in therapy lines, evidence relevant to contemporary practice is increasingly limited. The American Society for Blood and Marrow Transplantation (ASBMT), Center for International Blood and Marrow Transplant Research (CIBMTR), and European Society for Blood and Marrow Transplantation (EBMT) jointly convened an expert panel with diverse expertise and geographical representation to formulate consensus recommendations regarding the use of maintenance and/or consolidation therapies after auto-HCT in patients with lymphoma. The RAND-modified Delphi method was used to generate consensus statements where at least 75% vote in favor of a recommendation was considered as consensus. The process included 3 online surveys moderated by an independent methodological expert to ensure anonymity and an in-person meeting. The panel recommended restricting the histologic categories covered in this project to Hodgkin lymphoma (HL), mantle cell lymphoma (MCL), diffuse large B-...Continue Reading

References

May 5, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Marinus H J van OersAnton Hagenbeek
Jun 11, 2011·Best Practice & Research. Clinical Haematology·Andrew R Rezvani, David G Maloney
Jul 21, 2011·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Truus TeunissenTineke A Abma
Jul 11, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·D Andrew LoblawUNKNOWN Americal Society of Clinical Oncology Clinical Practice Guidelines
Aug 10, 2012·The New England Journal of Medicine·H C Kluin-NelemansM H Dreyling
Oct 24, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christian GisselbrechtBertram Glass
Dec 13, 2012·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·M BauerK Schwartzman
Jul 1, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Carla CasuloJonathan W Friedberg
Aug 11, 2015·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Navneet S MajhailUNKNOWN American Society for Blood and Marrow Transplantation
Sep 9, 2015·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S A GrafA K Gopal
Oct 28, 2016·British Journal of Haematology·Christian W EskelundChristian H Geisler
Mar 25, 2017·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Liat VidalOfer Shpilberg
Apr 21, 2017·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Catherine ThieblemontBertrand Coiffier
Jun 14, 2017·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Anita D'SouzaMarcelo Pasquini
Sep 28, 2017·The New England Journal of Medicine·Steven Le GouillUNKNOWN LYSA Group
Oct 5, 2017·The New England Journal of Medicine·Robert MarcusWolfgang Hiddemann
Dec 12, 2017·The New England Journal of Medicine·Joseph M ConnorsUNKNOWN ECHELON-1 Study Group
Dec 16, 2017·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Carla CasuloMehdi Hamadani
Dec 26, 2017·The Lancet Oncology·Umberto Vitolo, Annalisa Chiappella
Mar 16, 2018·Bone Marrow Transplantation·Jakob R PasswegUNKNOWN European Society for Blood and Marrow Transplantation (EBMT)
Mar 28, 2018·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Bruce D ChesonLaurie H Sehn
Apr 2, 2018·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Vindi JurinovicOliver Weigert

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Citations

Mar 16, 2019·Expert Review of Hematology·Parastoo B DahiHillard M Lazarus
May 18, 2019·American Society of Clinical Oncology Educational Book·Alison J MoskowitzAnne W Beaven
Aug 7, 2020·Journal of the National Comprehensive Cancer Network : JNCCN·Aliza Gardenswartz, Mitchell S Cairo
Apr 29, 2020·Pharmacotherapy·Kathryn A CulosMichael Byrne
Dec 7, 2019·Hematology·Victor A Chow, Ajay K Gopal
Oct 14, 2020·Bone Marrow Transplantation·Leyre BentoUNKNOWN Lymphoma Working Party of the European Society for Blood and Marrow Transplantation (EBMT)
Jan 13, 2021·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nirav N Shah, Mehdi Hamadani
May 10, 2021·Transplantation and Cellular Therapy·Farah YassineMohamed A Kharfan-Dabaja
Mar 14, 2020·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Abraham S KanateMehdi Hamadani
Apr 24, 2021·Blood·Narendranath Epperla, Alex F Herrera
Aug 28, 2021·Transplantation and Cellular Therapy·Peter A RiedellSonali M Smith

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