PMID: 3769442Jan 1, 1986Paper

Major antigenic groups of rabies virus in Canada determined by anti-nucleocapsid monoclonal antibodies

Comparative Immunology, Microbiology and Infectious Diseases
W A WebsterK M Charlton

Abstract

A total of 123 rabies virus isolates from various geographical areas in Canada were characterized by a panel of 43 anti-nucleocapsid monoclonal antibodies. Four major antigenic groups are found in terrestrial mammals: "Canadian Arctic" from Ontario, Quebec and the Northwest Territories; "south-eastern Georgian Bay" from Ontario; "south mid-central skunk" from Alberta, Saskatchewan and Manitoba; and "Brook's, Alberta skunk" from a restricted area in Alberta. Bat isolates can be divided into 4 major antigenic groups: "B-1" in Eptesicus fuscus from Ontario; "B-2" in a variety of bat species from British Columbia eastward into Ontario; "B-3" in Myotis spp. from Ontario and New Brunswick; and "B-4" in E. fuscus from Alberta and Saskatchewan. A single case of bat to horse transmission of rabies virus is recorded. These street isolates are compared with isolates of fixed virus. Epidemiological aspects are discussed.

References

Jul 1, 1980·The Journal of Experimental Medicine·T J Wiktor, H Koprowski
Jan 1, 1982·Comparative Immunology, Microbiology and Infectious Diseases·L G Schneider
May 1, 1984·Annals of Internal Medicine·L J AndersonW G Winkler

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Citations

May 1, 1991·Journal of Virological Methods·K KulonenM Topi
Nov 13, 2004·Acta Veterinaria Scandinavica·Torill Mørk, Pål Prestrud
Aug 1, 2014·PLoS Neglected Tropical Diseases·James A EllisonCharles E Rupprecht
Jan 1, 2008·Journal of Infection and Public Health·Nevio Cimolai, Tomas Cimolai
Jan 1, 1993·The Journal of Applied Bacteriology·I R Poxton
May 1, 1987·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·C L Dolman, K M Charlton

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