Major Aseptic Revision Following Total Knee Replacement: A Study of 478,081 Total Knee Replacements from the Australian Orthopaedic Association National Joint Replacement Registry

The Journal of Bone and Joint Surgery. American Volume
Nicholas B JorgensenRichard N de Steiger

Abstract

Major revision is associated with less satisfactory outcomes, substantial complications, and added cost. Data from the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) were analyzed to identify factors associated with major aseptic revision (MAR) of primary total knee replacement (TKR). The cumulative percent major aseptic revision rate following all primary TKRs performed in Australia from September 1, 1999, to December 31, 2015, was assessed. Kaplan-Meier estimates of survivorship were utilized to describe the time to first revision. Hazard ratios (HRs) from Cox proportional hazard models, adjusted for age and sex, were utilized to compare revision rates. There were 5,973 MARs recorded from the total cohort of 478,081 primary TKRs. The cumulative percent MAR at 15 years was 3.0% (95% confidence interval [CI], 2.8% to 3.2%). Fixed bearings had a significantly lower rate of MAR at 15 years: 2.7% (95% CI, 2.4% to 2.9%) compared with 4.1% (95% CI, 3.8% to 4.5%) for mobile bearings (HR, 1.77 [95% CI, 1.68 to 1.86]; p < 0.001). Age had a significant effect on MAR rates, with a cumulative percent revision at 15 years for patients <55 years old of 7.8% (95% CI, 6.5% to 9.2%) compared with 1.0% for thos...Continue Reading

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Citations

Jul 31, 2020·Expert Review of Medical Devices·Vicente J León-MuñozFernando Santonja-Medina
Jul 23, 2020·The Journal of the American Academy of Orthopaedic Surgeons·David D ChristensenYale A Fillingham
Nov 4, 2020·The Journal of Arthroplasty·Glenn S SlickLucas E Nikkel
Nov 18, 2020·Knee Surgery & Related Research·Seung Hoon LeeYong Seuk Lee
Feb 26, 2021·Revista Brasileira De Ortopedia·José Ricardo Pécora, Valéria Romero
Apr 2, 2021·The Bone & Joint Journal·Liam Z YappChloe E H Scott
Dec 29, 2021·Current Reviews in Musculoskeletal Medicine·Liam Z YappChloe E H Scott

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