Major Changes in Head and Neck Staging for 2018

American Society of Clinical Oncology Educational Book
William M LydiattSnehal G Patel

Abstract

Oncologists should be aware of three major modifications and additions to staging head and neck cancer that became effective in 2018. Oral cavity cancers have the addition of depth of invasion; oropharyngeal cancers (OPCs) are now distinguished by the immunohistochemical stain, p16, into those that are associated with high-risk human papillomavirus and those that are not; and all sites except nasopharyngeal carcinoma and high-risk human papillomavirus OPC will now include the important parameter of extranodal extension. The rationale and emerging data supporting these changes are discussed in this article and the accompanying oral presentation at the 2018 ASCO Annual Meeting.

References

Nov 16, 2010·International Journal of Radiation Oncology, Biology, Physics·Chun-Ta LiaoTzu-Chen Yen
May 17, 2011·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Nicolas F SchlechtMichael B Prystowsky
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Feb 11, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Shao Hui HuangBrian O'Sullivan

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Citations

Sep 27, 2019·Frontiers in Oncology·Panagiota EconomopoulouAmanda Psyrri
Aug 23, 2020·Journal of Magnetic Resonance Imaging : JMRI·Chih-Hua Yeh
Aug 14, 2020·Ciência & saúde coletiva·Amanda Ramos da CunhaFernando Neves Hugo
Nov 28, 2020·Nature Reviews. Disease Primers·Daniel E JohnsonJennifer R Grandis
Dec 2, 2020·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Bharat A PanugantiJoseph Califano
Apr 10, 2020·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Renata FerrarottoNeil D Gross
Jan 28, 2021·Head and Neck Pathology·Osias Vieira de Oliveira FilhoFabrício Bitu Sousa
Mar 6, 2021·The International Journal of Biochemistry & Cell Biology·Jefferson Muniz de LimaSabrina Daniela da Silva
Apr 21, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Melek Karakurt Eryılmaz, Cengiz Kadıyoran
Apr 23, 2021·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Christian MirianTherese Ovesen
May 28, 2021·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Anthony J CmelakBarbara Burtness
Dec 2, 2021·Journal of Medical Imaging and Radiation Oncology·Madhavi ChilkuriJustin Smith

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