Major clinical research advances in gynecologic cancer in 2018

Journal of Gynecologic Oncology
Miseon KimJae Weon Kim

Abstract

Nineteen topics were selected as major clinical research advances in gynecologic oncology in 2018. For cervical cancer, the importance of human papillomavirus (HPV) testing alone as primary cervical cancer screening method and negative survival impact of minimally invasive surgery in early-stage cervical cancer were addressed. For ovarian cancer, cost-effectiveness of genetic testing to prevent cancer, use of analgesics and oral pill to reduce cancer risk, efficacy of secondary cytoreductive surgery and hyperthermic intraperitoneal chemotherapy, update in the use of poly (ADP-ribose) polymerase inhibitor, and efficacy of anti-angiogenic targeted treatments, including bevacizumab and tyrosine kinase inhibitors, were reviewed. For corpus cancer, sentinel lymph node mapping technique, adjuvant therapy in high-risk endometrial cancer (PORTEC-3), and targeted therapy in recurrent disease were covered. For the field of radiation oncology, survival outcomes of chemoradiation compared with chemotherapy alone in metastatic cervical cancer and new findings regarding the use of neoadjuvant chemotherapy in locally advanced cervical cancer were introduced. Lastly, for breast cancer, the use of talazoparib in patients with germline BRCA1/2 m...Continue Reading

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Citations

May 1, 2020·Current Treatment Options in Oncology·Joanna GlajzerJacobus Pfisterer
May 21, 2020·The Journal of International Medical Research·Yijun FanLei Zhan
Jun 20, 2019·Frontiers in Oncology·Michiel Remmerie, Veerle Janssens
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Feb 21, 2021·Archives of Gynecology and Obstetrics·Gülşen Doğan DurdağHüsnü Çelik
Dec 12, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Soo Jin ParkJae-Weon Kim

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Methods Mentioned

BETA
hysterectomy
xenografts
fluorescence imaging

Clinical Trials Mentioned

NCT00565851
NCT02354586
NCT02657889
NCT02734004
NCT02715284
NCT00193739
NCT01973101

Software Mentioned

PINPOINT
MEDIOLA
PRIMA
SOLO

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