Major cluster of pediatric " true " primary chilblains during the COVID-19 pandemic: a consequence of lifestyle changes due to lockdown

Journal of the European Academy of Dermatology and Venereology : JEADV
Neri IriaLanari Marcello

Abstract

Over the last months, during the COVID-19 pandemic, a growing number of chilblain-like lesions was reported mainly in children, rarely in young adults. The relationship with SARS-CoV-2 infection was postulated, often without any laboratory, instrumental or clinical confirmation. The disclosure of information about chilblain-like lesions as a COVID-19 manifestation in social media has created concern in children's families and pediatricians OBJECTIVES: to verify whether the chilblain-like lesions were caused by SARS-CoV-2 infection. prospective study on a case series including children who presented with acral lesions at the Pediatric Dermatology Outpatient and Pediatric Emergency Unit of the University of Bologna, from April 1 to April 30, 2020. We reported demographical, laboratory and clinical features, history of close contact with COVID-19 patients, presence of similar skin lesions in other family members, precipitating and risk factors for chilblain onset. We evaluated 8 patients (5 females, 3 males) aged between 11 and 15 years. We excluded acute or previous SARS-CoV-2 infection with RT-PCR nasopharyngeal swab, serum antibody levels using chemiluminescent immunoassays. Other acute infections causing purpuric lesions at th...Continue Reading

References

Jan 1, 1974·Archives of Dermatology·R J Coskey, A H Mehregan
Nov 17, 2001·Journal of the American Academy of Dermatology·B CribierE Grosshans
Sep 6, 2005·Pediatrics·Tamara D SimonJ Roger Hollister
Nov 16, 2006·Acta Dermato-venereologica·Kaare Weismann, Frederik Grønhøj Larsen
Dec 5, 2009·The American Journal of Medicine·Shraddha Prakash, Michael H Weisman
Jan 30, 2013·Journal of Paediatrics and Child Health·Nicholas Larkins, Kevin J Murray
Dec 7, 2019·VASA. Zeitschrift für Gefässkrankheiten·Astrid NyssenJean-Claude Wautrecht
Jan 30, 2020·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Victor M CormanChristian Drosten
Mar 13, 2020·The New England Journal of Medicine·Weiyong LiuYingle Liu
Apr 22, 2020·Pediatric Dermatology·Giovanni GenoveseAngelo V Marzano
Apr 23, 2020·The New England Journal of Medicine·Alvaro Coronado MunozKonstantinos Boukas
Apr 25, 2020·International Journal of Dermatology·Nerea LandaTeresa Aguirre
Apr 25, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·T A DuongJ D Bouaziz
Apr 25, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·S RecalcatiF Fantini
Apr 28, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·J D BouazizM Rybojad
Apr 28, 2020·Journal of the American Academy of Dermatology·Diego Fernandez-NietoDaniel Ortega-Quijano
Apr 28, 2020·Journal of the American Academy of Dermatology·Poonkiat SuchonwanitChaninan Kositkuljorn
Apr 29, 2020·Anales De Pediatría·Miriam Morey-OlivéVicenç García-Patos
May 7, 2020·Pediatric Dermatology·Cristiana ColonnaCarlo Gelmetti

❮ Previous
Next ❯

Citations

Sep 1, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·M BaeckA Herman
Aug 21, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·I NeriA Guglielmo
Feb 26, 2021·Current Allergy and Asthma Reports·Désirée Larenas-LinnemannMirna Eréndira Toledo-Bahena
Feb 2, 2021·Clinical and Experimental Dermatology·M Baeck, A Herman
Mar 3, 2021·Journal of the European Academy of Dermatology and Venereology : JEADV·I NeriC Misciali
Mar 15, 2021·Mayo Clinic Proceedings·Mark A CappelDavid A Wetter
Apr 15, 2021·Journal of Cutaneous Medicine and Surgery·Nadia KashetskyJames Bergman
May 12, 2021·Clinics in Dermatology·Merav KoschitzkyNanette Silverberg
Sep 22, 2021·Journal of the European Academy of Dermatology and Venereology : JEADV·V Sánchez-GarcíaJ M Ramos-Rincón
Oct 21, 2021·Current Opinion in Pediatrics·James Ellis Dinulos, James Gary Dinulos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.