Major role of NAD-dependent lactate dehydrogenases in aerobic lactate utilization in Lactobacillus plantarum during early stationary phase

Journal of Bacteriology
Philippe GoffinPascal Hols

Abstract

NAD-independent lactate dehydrogenases are commonly thought to be responsible for lactate utilization during the stationary phase of aerobic growth in Lactobacillus plantarum. To substantiate this view, we constructed single and double knockout mutants for the corresponding genes, loxD and loxL. Lactate-to-acetate conversion was not impaired in these strains, while it was completely blocked in mutants deficient in NAD-dependent lactate dehydrogenase activities, encoded by the ldhD and ldhL genes. We conclude that NAD-dependent but not NAD-independent lactate dehydrogenases are involved in this process.

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Citations

Sep 7, 2007·Applied Microbiology and Biotechnology·Cuiqing MaPing Xu
Apr 2, 2013·World Journal of Microbiology & Biotechnology·A GuidoneE Parente
Apr 7, 2010·Applied and Environmental Microbiology·Marc J A StevensMichiel Kleerebezem
Dec 5, 2006·Applied and Environmental Microbiology·Jolanda M LambertMichiel Kleerebezem
Jan 31, 2007·Applied and Environmental Microbiology·Victor LaderoPascal Hols
Nov 28, 2007·Journal of Bacteriology·Tobias GeorgiVolker F Wendisch
Oct 15, 2013·Journal of Bioscience and Bioengineering·Saowanit TongpimKenji Sakai
Mar 3, 2010·Environmental Microbiology·Herwig BachmannJohan E T van Hylckama Vlieg
Aug 19, 2011·Biotechnology Advances·Chao GaoPing Xu
Apr 28, 2016·International Journal of Food Microbiology·Tharalinee Ua-ArakRudi F Vogel
Jun 22, 2014·Trends in Microbiology·Tianyi JiangPing Xu
Jun 7, 2016·Environmental Microbiology Reports·Yingxin ZhangPing Xu
Jan 13, 2017·Gut Microbes·Ulla G KnausFilipe Branco Dos Santos
Oct 29, 2014·Journal of Bacteriology·Benoît DesguinPascal Hols
Jun 20, 2017·Applied and Environmental Microbiology·Blandine DavidPascal Hols
Aug 24, 2017·FEMS Microbiology Reviews·Benoît DesguinPascal Hols
Dec 29, 2020·Journal of the Science of Food and Agriculture·Cristina MarzoAna Blandino
Feb 2, 2020·New Biotechnology·Margarida Ribau TeixeiraMaria A M Reis

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