Major surgery in infants weighing less than 1,500 grams

American Journal of Surgery
J H SeashoreG S Kopf

Abstract

From 1979 through 1981, 64 premature infants who weighed less than 1,500 g underwent 68 operations and 52 survived (81 percent). Twenty-six of 31 infants who weighed less than 1,000 g (84 percent) and 26 of 33 infants who weighed between 1,000 and 1,500 g survived (84 and 79 percent, respectively). The most common operation was ligation of a patent ductus arteriosus in 53 infants, of whom 43 survived (81 percent). Ten infants were operated on for necrotizing enterocolitis and 7 survived (70%). Four of five infants (80 percent) survived other major operations. Factors which influence survival include appropriate timing of operation, preoperative and postoperative mechanical ventilation, and parenteral nutrition. Intraoperative management includes short-duration anesthesia, continuous monitoring of vital signs, and judicious use of small amounts of amnestic and neuromuscular blocking agents combined with low fractional inspired oxygen concentration to reduce the risk of oxygen toxicity. Utilizing these principles, the survival rate compared favorably with the survival rate of all premature infants, which establishes that major surgery can be undertaken with only moderate risk in the infant with very low birth weight.

References

Sep 2, 1976·The New England Journal of Medicine·M A HeymannN H Silverman
Oct 1, 1972·The Journal of Pediatrics·L O LubchencoJ V Brazie
Jan 28, 1982·The New England Journal of Medicine·R L Williams, P M Chen

❮ Previous
Next ❯

Citations

May 1, 1984·Canadian Anaesthetists' Society Journal·C F Ward
Aug 1, 1984·Archives of Disease in Childhood·E M Kiely
Dec 1, 1983·Journal of Pediatric Surgery·R J Touloukian, G J Smith
Feb 1, 1987·Journal of Pediatric Surgery·J P GertlerR J Touloukian
Aug 20, 2008·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·M W FreundJ Strengers

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved