PMID: 2512045Jan 1, 1989Paper

Major surgery in von Willebrand's disease

Clinical and Laboratory Haematology
I DokalJ Hows

Abstract

Two patients with von Willebrand's disease underwent major surgery, the first had aortic valve replacement and the second a total hip replacement. Clinically, the best practical test for monitoring the dose of cryoprecipitate necessary to maintain haemostasis was the bleeding time. The response to coagulation factor replacement in von Willebrand's disease is extremely variable, and it is necessary to maintain close coagulation monitoring until the patient's surgical condition is satisfactory for discharge from hospital.

References

May 1, 1978·The Annals of Thoracic Surgery·C B WrightJ A Snow
Apr 1, 1979·The Australian and New Zealand Journal of Surgery·D D MaJ Lau
Mar 1, 1976·The American Journal of Medicine·D Green, E V Potter

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Citations

Jan 1, 1995·Acta Oto-laryngologica. Supplementum·H OkuboJ Kusakari
Nov 2, 2005·Inflammopharmacology·K D Rainsford

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