Major whey proteins in donkey's milk: effect of season and lactation stage. Implications for potential dietary interventions in human diseases

Immunopharmacology and Immunotoxicology
Angela G D'AlessandroVincenzo De Leo

Abstract

According to current literature, donkey's milk has been suggested as a hypoallergenic substitute in children affected by cow's milk protein allergy as well as a promising nutraceutical for aged people. However, the biologically active components of donkey's milk have not yet completely elucidated. In this framework this study is aimed at measuring α-lactalbumin (α-LA), β-lactoglobulin (β-LG), and lysozyme (LYS), the principal whey proteins in donkey's milk, in relation to lactation stage and production season. Analysis were performed by reversed-phase high-performance liquid chromatography. α-LA, β-LG, and LYS resulted to be affected by lactation stage (P < 0.01) and production season (P < 0.01). Overall, the protein content was higher (0.01 > P < 0.05) during the first four lactation's months and decreased until the month 8. The β-LG was the major protein (1.75 mg mL(-1) as mean; peak 2.24 ± 0.09 mg mL(-1)), while the α-LA had a mean concentration of 1.32 mg mL(-1) and peaked at month 1 (1.57 ± 0.09 mg mL(-1)) and LYS (0.66 mg mL(-1) as mean) showed the highest value equal to 0.76 ± 0.03 mg mL(-1). The highest (P < 0.01) concentration of all proteins was recorded at spring (α-LA: 1.69 mL(-1); β-LG: 2.07 mL(-1); LYS: 0.76 mL(-1)).

References

Jan 1, 1979·The Journal of Pediatrics·J K Welsh, J T May
Feb 1, 1992·Acta Paediatrica·C Kunz, B Lönnerdal
Feb 1, 1992·Journal of Pediatric Gastroenterology and Nutrition·G IaconoV Balsamo
Sep 1, 1990·Biological Chemistry Hoppe-Seyler·J Godovac-ZimmermannL Napolitano
Feb 1, 1987·Journal of Dairy Science·H M FarrellJ A Enyeart
Apr 1, 1987·Biological Chemistry Hoppe-Seyler·J Godovac-ZimmermannH McKenzie
May 1, 1974·The Journal of Experimental Medicine·S GordonZ A Cohn
Nov 1, 1966·The Journal of Experimental Medicine·E F Osserman, D P Lawlor
Dec 20, 1982·Biochimica Et Biophysica Acta·R WeverR Boelens
Jun 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·L Businco, J Bellanti
Aug 24, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A CarroccioG Iacono
Aug 24, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·I SéloJ Wal
May 16, 2000·The Journal of Allergy and Clinical Immunology·L BusincoM Orlandi
Jul 6, 2000·Journal of Dairy Science·D A Clare, H E Swaisgood
Aug 17, 2000·Journal of Protein Chemistry·M HerrouinJ Léonil
Nov 9, 2000·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A CarroccioG Iacono
Mar 10, 2001·The British Journal of Nutrition·H S Gill, M L Cross
May 31, 2001·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·R C Aalberse, S O Stapel
Oct 19, 2001·European Journal of Biochemistry·D FessasF Bonomi
Dec 1, 2001·International Archives of Allergy and Immunology·K M JärvinenH A Sampson
Jan 15, 2002·Advances in Experimental Medicine and Biology·L G Sternhagen, J C Allen
May 29, 2003·Current Pharmaceutical Design·D A ClareH E Swaisgood
Jun 19, 2003·The American Journal of Clinical Nutrition·Bo Lönnerdal
Jun 15, 2004·International Journal of Food Microbiology·L VanniniM E Guerzoni
Jul 27, 2004·Proteomics·Guy MirandaPatrice Martin
Apr 15, 2005·Journal of Dairy Science·F Lara-VillosladaJ Xaus
Nov 16, 2006·Acta Dermato-venereologica·Kyung Ho LeeChul Jong Park
Jan 20, 2007·Journal of Dairy Science·H C LiuS J T Mao
Apr 17, 2007·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Giovanna MontiAmedeo Conti
Nov 16, 2007·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Daniela VitaGiovanni B Pajno
Nov 16, 2007·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Claudia Alessandri, Adriano Mari
Jul 11, 2009·Italian Journal of Pediatrics·Riccardina TesseLucio Armenio
Apr 15, 2010·Current Pharmaceutical Design·L AmatiE Jirillo
Oct 1, 2008·Animal : an International Journal of Animal Bioscience·C GiosuèC Torrisi

❮ Previous
Next ❯

Citations

Sep 12, 2012·Lipids in Health and Disease·Giovanni Martemucci, Angela Gabriella D'Alessandro
Dec 2, 2014·The Journal of Dairy Research·Angela Gabriella D'AlessandroGiovanni Martemucci

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Cell Wall Structure

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.

Bacterial Cell Wall Structure (ASM)

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.