Majority of children aged 3 years and above can reliably inhale through the Clickhaler

Pediatric Pulmonology
Shaique M IqbalM L Everard

Abstract

Guidelines suggest that pressurized metered dose inhalers (pMDI) plus spacers are the delivery system of choice for children. However, they are bulky, which makes them inconvenient. It was suggested that the smaller dry-powder inhalers (DPIs) may be suitable for delivering short-acting bronchodilators to preschool children. This study considered whether preschool children could reliably generate sufficient inspiratory flows to use the Clickhaler DPI. Twenty-seven asthmatic and 34 nonasthmatic children, aged 2-5 years, were recruited. Following training, they were asked to inhale four times through a Clickhaler flow monitoring system, twice "steadily" and twice "forcefully." Inspiratory flow data were collected during each inhalation. Of the 3-, 4-, and 5-year-old asthmatics, 62.5, 100, and 100%, respectively, could reliably differentiate between inhaling and exhaling through the DPI. For nonasthmatics, the figures were 66, 60, and 88%, respectively. All but one of the children who understood the instructions generated a PIF of greater than 15 l/min (range, 13.9-88.3 l/min and 21.2-84.5 l/min in asthmatic and nonasthmatic children, respectively). These data indicate that the majority of children aged 3 years and above could reli...Continue Reading

References

Mar 1, 1990·Archives of Disease in Childhood·S PedersenG Fuglsang
Oct 6, 1997·The European Respiratory Journal·S G DevadasonP N Le Souëf
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Feb 12, 2002·Pediatric Pulmonology·Chris O'CallaghanPeter Weller
Feb 5, 2003·Pediatric Pulmonology·Mark Parry-BillingsChristopher O'Callaghan

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Citations

Aug 6, 2004·Journal of Aerosol Medicine : the Official Journal of the International Society for Aerosols in Medicine·Mark L Everard
Nov 4, 2005·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·A MoriceUNKNOWN Trumpet Study Group
Oct 16, 2019·Journal of Aerosol Medicine and Pulmonary Drug Delivery·Andrew R ClarkRajiv Dhand

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