Making animals alcoholic: shifting laboratory models of addiction

Journal of the History of the Behavioral Sciences
Edmund Ramsden

Abstract

The use of animals as experimental organisms has been critical to the development of addiction research from the nineteenth century. They have been used as a means of generating reliable data regarding the processes of addiction that was not available from the study of human subjects. Their use, however, has been far from straightforward. Through focusing on the study of alcoholism, where the nonhuman animal proved a most reluctant collaborator, this paper will analyze the ways in which scientists attempted to deal with its determined sobriety and account for their consistent failure to replicate the volitional consumption of ethanol to the point of physical dependency. In doing so, we will see how the animal model not only served as a means of interrogating a complex pathology, but also came to embody competing definitions of alcoholism as a disease process, and alternative visions for the very structure and purpose of a research field.

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Citations

Oct 25, 2016·The Spanish Journal of Psychology·Gabriel Ruiz, Natividad Sánchez
Jun 6, 2020·Annual Review of Biomedical Engineering·W Andrew PruettRobert L Hester
Jun 27, 2019·Alcoholism, Clinical and Experimental Research·Meyer D Glantz
Apr 14, 2021·Cognitive, Affective & Behavioral Neuroscience·M VigoritoA J Pra Sisto

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