PMID: 7029733Nov 14, 1981Paper

Malaria 'breakthroughs' and resistance to chloroquine in Africa. Case reports

South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
J L Mahoney

Abstract

Four cases of Plasmodium falciparum malaria are presented. These cases are typical of chloroquine resistant malaria, with their pattern of 'breakthrough' malaria despite chloroquine prophylaxis, absence of response to therapeutic doses of chloroquine and recrudescence of the malarial parasites. These cases should alert physicians in other parts of the world, who may have to treat travelers from Central and West Africa, and particularly from the Ivory Coast, to the possibility that the malaria contracted in these areas may be chloroquine-resistant. The most effective drug in these cases appears to be a combination of sulphadoxine and pyrimethamine.

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Related Papers

The American Journal of Tropical Medicine and Hygiene
R A Eke
The Journal of Tropical Medicine and Hygiene
A A SandoshamA R Ali
South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
R W NieuwveldF H Spracklen
European Journal of Clinical Pharmacology
Jens RengelshausenIngeborg Walter-Sack
© 2021 Meta ULC. All rights reserved