Abstract
The epidemiological coexistence of schistosomiasis and malaria is frequently observed in developing countries. Co-infection with malaria in children could influence the development of acquired immunity associated with the resistance or the pathology of schistosomiasis. In the present study, performed during May to June 1996 in Senegal, the humoral immune response to Schistosoma haematobium 28 kDa glutathione S-transferase (Sh28GST) vaccinal antigen and to soluble egg antigens (SEA) has been evaluated in individuals infected by S. haematobium. Specific immunoglobulin G3 (IgG3) and IgE responses were significantly higher in co-infected children with Plasmodium falciparum compared with children infected with S. haematobium only. In addition, circulating levels of interferon-gamma (IFN-gamma), interleukin-10 (IL-10), and soluble tumor necrosis factor receptor II (sTNF-RII), 3 parameters associated with schistosomiasis morbidity, were significantly increased in co-infected children. Taken together, this study indicated that malaria co-infection can both influence the acquired specific immune response to schistosome antigens and unbalance the regulation of inflammatory factors closely involved in schistosomiasis pathology.
References
Sep 1, 1990·Journal of Clinical Microbiology·C AuriaultJ L Neyrinck
Jun 1, 1994·Clinical Immunology and Immunopathology·C WenischW Wernsdorfer
Feb 1, 1994·Clinical and Experimental Immunology·F PeyronJ Banchereau
Jan 1, 1997·Infection and Immunity·P PerlmannM Troye-Blomberg
Oct 10, 1998·Parasite Immunology·P EsterreJ Roux
May 6, 1999·The Journal of Infectious Diseases·S M MontenegroT A Wynn
Sep 9, 1999·The Journal of Infectious Diseases·N P DayM Ho
Jan 19, 2000·Immunology Today·P G Fallon
Apr 12, 2000·Parasite Immunology·F MutapiM E Woolhouse
May 24, 2000·The Journal of Infectious Diseases·F RemouéG Riveau
Apr 18, 2001·International Archives of Allergy and Immunology·A CapronG Riveau
May 10, 2001·Trends in Parasitology·J H OumaA E Butterworth
May 22, 2001·Clinical and Experimental Immunology·F RemouéG Riveau
Oct 25, 2002·Annals of Tropical Medicine and Parasitology·S SowB Gryseels
Sep 9, 2004·Current Opinion in Infectious Diseases·Birgitte J Vennervald, David W Dunne
Citations
Jun 23, 2012·Transactions of the Royal Society of Tropical Medicine and Hygiene·Jean Biram SarrFranck Remoue
Aug 5, 2011·Parasitology·Natsuko ImaiFrancisca Mutapi
Sep 9, 2004·Current Opinion in Infectious Diseases·Birgitte J Vennervald, David W Dunne
Jan 11, 2013·Proceedings. Biological Sciences·Joanne LelloMark E Viney
Feb 21, 2008·Infection and Immunity·Shona WilsonDavid W Dunne
Sep 22, 2006·Infection and Immunity·Kirsten E LykeMarcelo B Sztein
Feb 19, 2010·BMC Immunology·Karen J Fairlie-ClarkeJudith E Allen
Aug 1, 2012·PLoS Neglected Tropical Diseases·Lia S FloreyMark L Wilson
Sep 22, 2010·PloS One·Tamsir O DialloGilles Riveau
Feb 22, 2012·PloS One·Kirsten E LykeMarcelo B Sztein
Jun 14, 2012·PloS One·Kirsten E LykeMarcelo B Sztein
Mar 18, 2005·Parasite Immunology·D W Dunne, E M Riley
Feb 1, 2005·Parasite Immunology·T O DialloG Riveau
Oct 14, 2014·Mediators of Inflammation·Juan Camilo Sánchez-ArcilaJoseli Oliveira-Ferreira
Jan 20, 2009·Parasite Immunology·S WilsonD W Dunne
Apr 18, 2015·European Journal of Microbiology & Immunology·B WangalaC Köhler
Jul 7, 2015·PLoS Pathogens·Stephanie M CoomesMark S Wilson
Dec 11, 2013·The American Journal of Tropical Medicine and Hygiene·Magali LemaitreMichel Cot
Feb 17, 2018·Frontiers in Immunology·Kirsten E LykeMarcelo B Sztein
Sep 1, 2005·Current Opinion in Allergy and Clinical Immunology·Kathleen C BarnesPeisong Gao
Feb 14, 2012·Current Opinion in HIV and AIDS·Shona Wilson, David W Dunne
Sep 14, 2011·PLoS Neglected Tropical Diseases·Shona WilsonDavid W Dunne
Aug 15, 2014·SpringerPlus·Ulysse Ateba NgoaAyola Akim Adegnika
Dec 9, 2021·Microbiology Spectrum·Rebeca SantanoCarlota Dobaño