Malaria pigment paralyzes dendritic cells.

Journal of Biology
Britta C Urban, Stephen Todryk

Abstract

The capacity of malarial infection to suppress the patient's immune responses both to the parasite and to other antigens has long puzzled researchers. A prime suspect, the parasite-produced pigment hemozoin, has now been clearly shown to mediate immunosuppression by inhibiting dendritic cell activity.

References

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Citations

Sep 3, 2013·Asian Pacific Journal of Tropical Biomedicine·Chuchard Punsawad
Sep 22, 2006·Infection and Immunity·Lutz P BreitlingAdrian J F Luty
Jul 3, 2013·BMC Public Health·Dennison KizitoAlison M Elliott
Nov 24, 2011·International Journal of Biological Sciences·Laura Adalid-PeraltaEdda Sciutto
Feb 20, 2010·Journal of Biomedicine & Biotechnology·Marion M ChanDunne Fong
Sep 22, 2009·Drug Metabolism Reviews·Eugene D Weinberg, Jym Moon
Dec 15, 2015·FEMS Microbiology Reviews·Katrien DeroostPhilippe E Van den Steen
Feb 28, 2007·Cellular Microbiology·Daniel CarapauAna Rodriguez
May 9, 2012·Malaria Research and Treatment·Rosangela FritaThomas Hänscheid
Sep 28, 2007·The Lancet Infectious Diseases·Thomas HänscheidMartin P Grobusch
Nov 26, 2014·Japanese Journal of Infectious Diseases·Iva ChristovaMariana Stoycheva
Dec 26, 2016·International Journal for Parasitology·Shu-Hua Xiao, Jun Sun
Dec 12, 2007·Seminars in Immunopathology·Catherine RopertRicardo T Gazzinelli
Feb 12, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Juliette DiouMichel J Tremblay
Aug 3, 2013·BioFactors·Ariane TybergheinPhilippe E Van den Steen
Jan 23, 2015·Tropical Medicine & International Health : TM & IH·Angela NalwogaRobert Newton
Aug 30, 2014·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Harriet MpairweAlison M Elliott
Apr 27, 2018·Microbiology and Molecular Biology Reviews : MMBR·Hyun Jae LeeAubrey J Cunnington
Jun 21, 2017·Journal of Tropical Medicine·Alberto Tobón-CastañoCecilia Giraldo Castro
Apr 6, 2021·Frontiers in Immunology·Carlos Lamsfus CalleBenjamin Mordmüller

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