MALDI Mass Spectrometry Profiling and Imaging Applied to the Analysis of Latent Fingermarks

Methods in Molecular Biology
Robert Bradshaw

Abstract

Latent fingermarks are derived from a transfer of material from the fingertips to a surface upon contact. Traditionally, fingermarks are employed for biometric identification of individuals based on matching of the pattern of the ridges. However, in recent years, there has been a stark increase in the use of advanced analytical techniques in order to obtain additional information, specifically the chemical composition of the residue. Understanding the complexity of the endogenous and exogenous content of fingermarks could be extremely useful in allowing further development of enhancement techniques currently used in forensic scenarios by identifying potential target molecules. This chemical information could also potentially provide invaluable information on the lifestyle of an individual, including their activities prior to depositing a mark.An analytical tool that has gained notable popularity in this novel area of research is matrix-assisted laser desorption/ionisation mass spectrometry (MALDI MS). This technique can either be employed for rapid chemical profiling or imaging of fingermarks to detect chemical species contained within the residue, with the latter also allowing for physical reconstruction of the fingermark ridg...Continue Reading

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