Male breast cancer: a retrospective study from a regional cancer center in northern India

Journal of Surgical Oncology
Nootan K ShuklaM C Misra

Abstract

Over a 7-year period from 1987 to 1993, 41 male breast cancer patients were seen in the breast cancer clinic of the Institute Rotary Cancer Hospital (IRCH) at the All India Institute of Medical Sciences (AIIMS). Their mean age was 54.2 years; and duration of symptoms ranged from 1 to 84 months with a mean of 15.1 months. Breast lump was the commonest presenting symptom. Fine needle aspiration cytology (FNAC) was the commonest diagnostic procedure. The TNM stage distribution was stage I, 5; stage II, 13; stage III, 17; and stage IV, 6. Radical mastectomy (25/36) was the commonest surgical procedure. Locoregional radiotherapy was given in 15 patients. Thirty patients received systemic adjuvant therapy (chemotherapy or tamoxifen, or a combination of the two). Local or distant recurrence occurred in 8 patients (8/31, 28.3%). Actuarial overall and disease-free survival was 100% and 80.1% at 2 years and 91.7% and 66.7% at 4 years, respectively. On univariate analysis, axillary lymph node status and age were found to affect disease-free survival significantly. Advanced stage of disease at presentation is common in Indian patients and will continue to influence treatment policies. Neoadjuvant chemotherapy needs to be evaluated for loca...Continue Reading

References

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Citations

Feb 22, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·K J Ruddy, E P Winer
Mar 11, 2016·Indian Journal of Cancer·A GogiaB K Mohanti
Feb 25, 2009·Journal of Surgical Oncology·Anjita PandeyHari S Shukla
Oct 13, 2006·Breast Cancer Research and Treatment·A AgrawalJ F R Robertson

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