Male gonadal dose of ionizing radiation delivered during X-ray examinations and monthly probability of pregnancy: a population-based retrospective study

BMC Public Health
Sandra Sinno-TellierRemy Slama

Abstract

Male gonadal exposure to ionizing radiation may disrupt spermatogenesis, but its influence on the fecundity of couples has been rarely studied. We aimed to characterize the influence of male gonadal dose of ionizing radiation delivered during radiodiagnostic on the monthly probability of pregnancy. We recruited a random sample of women who retrospectively described 1110 periods of unprotected intercourse beginning between 1985 and 1999 and leading either to a live birth or to no pregnancy; their duration was censored after 13 months. The male partner answered a telephone questionnaire on radiodiagnostic examinations. We assigned a mean gonadal dose to each type of radiodiagnostic examination. We defined male dose for each period of unprotected intercourse as the sum of the gonadal doses of the X-ray examinations experienced between 18 years of age and the date of discontinuation of contraception. Time to pregnancy was analysed using a discrete Cox model with random effect allowing to estimate hazard ratios of pregnancy. After adjustment for female factors likely to influence fecundity, there was no evidence of an association between male dose and the probability of pregnancy (test of homogeneity, p = 0.55). When compared to cou...Continue Reading

References

Feb 1, 1988·The British Journal of Radiology·G ContentoP C Shrimpton
Apr 1, 1988·Health Physics·C MacciaF Fagnani
Nov 19, 1987·The New England Journal of Medicine·J ByrneK Bragg
Sep 1, 1986·American Journal of Epidemiology·D D BairdC R Weinberg
Feb 1, 1987·The British Journal of Radiology·R PadovaniG Gozzi
Jan 1, 1995·Environmental and Molecular Mutagenesis·B L SailerD P Evenson
Dec 1, 1995·British Journal of Obstetrics and Gynaecology·L SchmidtP Helm
Dec 1, 1996·Journal of Epidemiology and Community Health·H O DickinsonJ Smith
Feb 24, 1999·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·P C ShrimptonD Hart
Jun 4, 1999·American Journal of Epidemiology·M SalasB H Stricker
Oct 26, 1999·The Journal of Experimental Zoology·A Ahmadi, S C Ng
Oct 6, 2000·Epidemiology·M SallménM Nurminen
Mar 3, 2001·Human Reproduction·J F Velez de la CalleP F Thonneau
Jul 14, 2001·Occupational and Environmental Medicine·P DoyleV Beral
May 7, 2002·International Journal of Cancer. Journal International Du Cancer·Heather O Dickinson, Louise Parker
Apr 4, 2003·American Journal of Epidemiology·Amy Berrington de GonzalezPeter D Inskip
May 3, 2003·American Journal of Epidemiology·Rémy SlamaWolfgang Härdle
May 30, 2003·Human Reproduction·Steffen LoftJens Peter Bonde
Jul 2, 2003·Human Reproduction·Nunziatina BurrelloAldo E Calogero
Dec 15, 2004·Urology·François A GiulianoAnne Solesse de Gendre
Jun 24, 2005·American Journal of Epidemiology·Michael JoffeTina Kold Jensen

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Citations

Sep 21, 2013·Epidemiology·Rémy SlamaRadim Sram

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Methods Mentioned

BETA
X-ray
contraception

Software Mentioned

SE
Stata

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