PMID: 37692Jul 1, 1979

Male hypospadias, 625 cases, associated malformations and possible etiological factors

Acta paediatrica Scandinavica
J Svensson


Records from 625 patients with hypospadias have been reviewed, with reference to associated malformations. Cryptorchidism was found to be the most common associated malformation and was present in 6% of cases with hypospadias. The highest incidence of cryptorchidism was found in the more severe forms of hypospadias. Other concomitant genital malformations, such as bifid scrotum, hypoplasia of penis and remnants of the Müllerian system showed the same pattern. The recorded incidence of bifid scrotum and hypoplasia of the penis was 4% and 8% respectively. A high incidence of abnormalities in the lower urinary tract was found; 50% of 84 patients investigated. The hypothesis of hypospadias being a result of testicular hormone insufficiency is discussed.


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Sep 1, 1990·Journal of Medical Genetics·C StollB Dott
Jul 20, 2010·The Journal of Urology·Gregory E TasianL S Baskin
Jul 1, 1982·Urology·R ShafirP Jonas
May 1, 1985·American Journal of Medical Genetics·T J LeungB McGillivray
Jan 1, 1986·Acta Paediatrica Scandinavica. Supplement·B KällénO Mutchinick
Jan 1, 1982·Acta Paediatrica Scandinavica. Supplement·B Källén, J Winberg
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Jan 25, 2011·Molecular and Cellular Endocrinology·N KalfaC Sultan
May 15, 2016·Annales de chirurgie plastique et esthétique·N BoudaoudC Francois
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Jul 30, 2017·Birth Defects Research·M Hassan ToufailyLewis B Holmes
Sep 1, 1984·Journal of Andrology·C EilD L Loriaux


Dec 1, 1976·The Journal of Urology·J Rajfer, P C Walsh
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Sep 1, 1976·Plastic and Reconstructive Surgery·R C WrayP M Weeks
Nov 1, 1976·The Journal of Urology·B FallonC E Horton
Jan 1, 1975·Scandinavian Journal of Plastic and Reconstructive Surgery·L Avellán
Mar 1, 1976·Clinical Genetics·R B Lowry, M R Kliman
Jun 1, 1971·Journal of Medical Genetics·Y C Chen, P V Woolley
Mar 1, 1973·The Journal of Endocrinology·D R Abramovich, P Rowe
Jan 1, 1974·The Journal of Clinical Endocrinology and Metabolism·P K Siiteri, J D Wilson
Apr 1, 1974·The Journal of Clinical Endocrinology and Metabolism·F I ReyesC Faiman
Oct 1, 1959·Plastic and Reconstructive Surgery and the Transplantation Bulletin·J F ROSSW K LINDSAY

Related Concepts

Penile Hypospadias
Entire Lower Urinary Tract
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Testicular Hormones
Congenital Absence of Both Testes
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