Male infertility: recent developments

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Eberhard Nieschlag

Abstract

Although male reproductive functions are impaired in about half of the infertile couples seeking offspring, even today the examination and treatment of the male partner continues to be neglected. Despite the lack of evidence for a "sperm crisis", so highly touted in the press, the public remains worried, while the fact that male fertility declines beyond the age of 40 years and is accompanied by increasing genetic risks for the offspring goes largely unnoticed. In addition to a thorough physical examination supplemented by imaging techniques such as ultrasonography of the scrotal organs, semen analysis according to WHO guidelines, hormone determinations, and cyto- and molecular genetic analyses form part of the routine investigation of the infertile male. Few disorders have become subjects of rational treatment, such as hypogonadotropic hypogonadism with gonadotropins or GnRH, treatment of sexually transmitted diseases by antibiotics, and microsurgical reconstruction of blocked seminal ducts. Early treatment of maldescended testes in boys or changing lifestyle (e.g., discontinuation of smoking) are important preventive measures. In the age of evidence-based medicine, most empirical treatments have been demonstrated to be ineffe...Continue Reading

References

Sep 12, 1992·BMJ : British Medical Journal·E CarlsenN E Skakkebaek
Nov 26, 1999·Human Reproduction·A Kamischke, E Nieschlag
Jul 9, 2002·Human Reproduction Update·Egbert R te Velde, Peter L Pearson
Jun 13, 2003·Fertility and Sterility·Mohamed A M Hassan, Stephen R Killick
Jun 13, 2003·Fertility and Sterility·Michael ZitzmannEberhard Nieschlag
Jun 12, 2004·Human Reproduction Update·Bianca Kühnert, Eberhard Nieschlag
Aug 24, 2006·The Journal of Clinical Endocrinology and Metabolism·Michael ZitzmannEberhard Nieschlag
Sep 13, 2006·Human Reproduction·C H Ramlau-HansenJ P Bonde
Mar 1, 2007·Acta Paediatrica·E Martin RitzénH Virtanen
Jan 29, 2008·Fertility and Sterility·Armand ZiniJamie Libman
Feb 21, 2008·Reproductive Biomedicine Online·Manuela SimoniEberhard Nieschlag
Mar 14, 2008·Andrologia·F R Ochsendorf
Dec 11, 2008·The Journal of Clinical Endocrinology and Metabolism·Peter Y LiuDavid J Handelsman
Aug 22, 2009·Human Reproduction Update·Gideon A Sartorius, Eberhard Nieschlag
Sep 2, 2009·Clinical Endocrinology·Robert K Semple, A Kemal Topaloglu
Nov 26, 2009·Human Reproduction Update·Trevor G CooperKirsten M Vogelsong
Mar 27, 2010·Fertility and Sterility·Jan W van der SteegUNKNOWN Collaborative Effort for Clinical Evaluation in Reproductive Medicine Study Group
Apr 17, 2010·Human Reproduction·Egbert te VeldeDik Habbema
Jul 9, 2010·International Journal of Andrology·F TüttelmannE Nieschlag
Jan 6, 2011·Der Urologe. Ausg. A·S KlieschH M Behre
Mar 15, 2011·Best Practice & Research. Clinical Endocrinology & Metabolism·Aleksander Giwercman, Yvonne Lundberg Giwercman
May 3, 2011·Human Reproduction·C MallidisS Schlatt
Nov 16, 2011·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Kimberly LiuAllison Case
May 29, 2012·Fertility and Sterility·Con MallidisEberhard Nieschlag
Jul 13, 2012·Human Reproduction·A P FerrarettiUNKNOWN Consortium for European Society of Human Reproduction and Embryology (ESHRE)
Sep 25, 2012·Asian Journal of Andrology·Eberhard Nieschlag, Alexander Lerchl
Jan 8, 2013·Asian Journal of Andrology·Harry Fisch, Stephen R Braun

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.