"Male lumpectomy": focal therapy for prostate cancer using cryoablation

Urology
Gary OnikJeff Brady

Abstract

The introduction of breast-sparing surgery (ie, "lumpectomy") revolutionized the management of breast cancer. The use of lumpectomy showed that quality of life could be optimized without compromising treatment efficacy. Complications of prostate cancer treatment, including impotence and incontinence, adversely alter the male self-image similarly to the way the loss of a breast does for a woman. Traditional thinking holds that prostate cancer is multifocal and therefore is not amenable to focal treatment. However, histopathologic findings from published data have indicated that up to 25% of prostate cancers are solitary and unilateral. Furthermore, the significance of minute secondary cancers might be minimal. These observations raise the question of whether certain patients can be identified and treated with a limited "lumpectomy." In this study, focal cryoablation has been used to ablate the area of known cancer as determined by staging biopsies. The serum prostate-specific antigen (PSA) concentration was obtained every 3 months for 2 years and every 6 months thereafter. American Society for Therapeutic Radiology Oncology (ASTRO) criteria for PSA recurrence were used. A total of 55 patients with > or = 1 year of follow-up had ...Continue Reading

References

Sep 7, 2002·Urology·Daniel B RukstalisFernando U Garcia
Dec 19, 2003·The Urologic Clinics of North America·Edward M Messing, Ian Thompson
Oct 18, 2005·BJU International·E David CrawfordPriya N Werahera

❮ Previous
Next ❯

Citations

May 14, 2014·Nature Reviews. Clinical Oncology·Laurence Klotz, Mark Emberton
Oct 5, 2011·Therapeutic Advances in Urology·Michael S BorofskySamir S Taneja
Apr 29, 2010·Current Urology Reports·Matvey Tsivian, Thomas J Polascik
Mar 25, 2011·Current Urology Reports·Christian G Chaussy, Stefan F Thüroff
Apr 7, 2010·Journal of Endourology·Christian G Chaussy, Stefan Thüroff
May 7, 2010·Journal of Endourology·Vladimir MouravievThomas J Polascik
Jun 11, 2010·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Luigi Mearini, Massimo Porena
Aug 16, 2008·World Journal of Urology·Hashim Uddin Ahmed, Mark Emberton
Oct 22, 2010·World Journal of Urology·U LindnerJ Trachtenberg
Jul 17, 2012·Urologic Oncology·G BozziniN Betrouni
Sep 8, 2010·Urologic Oncology·Emilie LecornetMark Emberton
Jan 20, 2009·The Journal of Urology·Basir TareenSamir S Taneja
Sep 27, 2008·The Journal of Urology·Richard J BabaianJ Brantley Thrasher
Oct 30, 2009·International Journal of Radiation Oncology, Biology, Physics·Hendrik IsbarnMarkus Graefen
Jun 27, 2009·Journal of Magnetic Resonance Imaging : JMRI·Sonal JosanKim Butts Pauly
Nov 13, 2014·World Journal of Urology·Ghassan A BarayanSimon Tanguay
Oct 27, 2015·Magnetic Resonance Imaging Clinics of North America·David A WoodrumLance A Mynderse
Jun 19, 2013·European Urology·Massimo ValerioThomas J Polascik
Mar 26, 2015·Polish journal of radiology·Mohammed AlkhorayefMaram A Fagiri
Sep 7, 2016·European Urology·Massimo ValerioMark Emberton
Mar 15, 2014·Current Opinion in Urology·Niccolò M Passoni, Thomas J Polascik
Apr 8, 2017·Clinical Radiology·D A WoodrumL A Mynderse
Jun 22, 2017·Expert Review of Anticancer Therapy·Kae Jack TayThomas J Polascik
Jan 15, 2014·Urologia·Massimo LazzeriGiorgio Guazzoni
Jun 6, 2018·Topics in Magnetic Resonance Imaging : TMRI·David A WoodrumLance A Mynderse
May 7, 2015·World Journal of Urology·Taimur T ShahHashim U Ahmed
Feb 7, 2009·Current Opinion in Urology·Judd W MoulThomas J Polascik
Feb 4, 2009·Current Opinion in Urology·Thomas J PolascikVladimir Mouraviev
Apr 9, 2009·Nature Reviews. Urology·Vladimir MouravievThomas J Polascik
Sep 16, 2010·Nature Reviews. Urology·Uri LindnerNathan Lawrentschuk
Feb 26, 2016·Abdominal Radiology·David A WoodrumLance A Mynderse
Dec 13, 2017·Current Opinion in Urology·Fuad F ElkhouryLeonard S Marks
Nov 5, 2014·Expert Review of Anticancer Therapy·Taimur Tariq ShahManit Arya
Jul 18, 2017·Clinical and Translational Imaging : Reviews in Nuclear Medicine and Molecular Imaging·Hossein Jadvar
Jun 27, 2014·Expert Review of Anticancer Therapy·Massimo ValerioHashim U Ahmed

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.