Male-to-Female Gender-Affirming Surgery Using Nile Tilapia Fish Skin as a Biocompatible Graft.

Journal of Minimally Invasive Gynecology
Álvaro Hernán RodríguezLeonardo Robson Pinheiro Sobreira Bezerra

Abstract

Insufficient penile skin is common during vaginoplasty for male-to-female transition. This issue may be compensated by a scrotal skin flap, with the drawback of hair growth [1]. In recent studies, Nile tilapia skin was successfully used for the surgical management of Mayer-Rokitansky-Küster-Hauser syndrome [2,3] and vaginal stenosis [4,5]. This study aims to describe a novel technique for primary vaginoplasty in male-to-female gender-affirming surgery using Nile tilapia skin as a biocompatible graft to ensure adequate vaginal depth. Stepwise demonstration of the procedure with narrated video footage. Transgender health clinic. A 29-year-old patient with gender dysphoria was referred to our office because of a desire for gender-affirming surgery. A physical examination revealed normal male genitalia with a 14-cm-long penis. Before surgery, approval from the institutional review board and written permission from the patient were obtained. After orchiectomy, penile disassembly, perineal dissection, and urethroplasty were performed, and a hollow Nile tilapia skin mold was prepared and sutured to the distal edge of the remaining penile skin. This structure was inverted, covering the newly created canal. The neocavity was then filled...Continue Reading

Citations

Apr 22, 2021·Andrology·Carmen KloerRachel Bluebond-Langner
May 26, 2021·Journal of Tissue Engineering and Regenerative Medicine·Yongsheng LiHairong Liu
Aug 1, 2021·Acta histochemica·Maria Elisa Quezado Lima VerdeAna Paula Negreiros Nunes Alves

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