Malignancies of the eyelid: a review of primary and metastatic cancers

International Journal of Dermatology
Mhair S DekmezianJaime A Tschen

Abstract

The eyelid can be the site of various malignant tumors, including epithelial, mesenchymal, lymphoproliferative, and endocrine neoplasms, all of which can present in unusual ways or mimic benign processes, often requiring biopsy for a definitive diagnosis. This review article presents a broad overview of some of the malignancies that have been reported to occur in eyelids, addressing clinical presentation and natural history, histologic and immunostaining characteristics, and genetic associations where relevant. The unique combination of functional importance, to protect and lubricate the eye, and cosmetic importance make management of eyelid lesions difficult. We describe a few of the diagnostic and treatment options that can be considered.

References

Oct 15, 1992·Cancer·S N Snow, G T Reizner
Nov 1, 1992·Journal of the American Academy of Dermatology·D J Gross, M Waner
Jan 1, 1992·Journal of the American Academy of Dermatology·R E KwaR L Moy
Oct 1, 1991·Journal of the American Academy of Dermatology·C W Lober, N A Fenske
May 1, 1989·Survey of Ophthalmology·L G Kass, A Hornblass
Jan 1, 1988·Surgical and Radiologic Anatomy : SRA·J PatrícioL Silveira
Nov 1, 1988·The Journal of Dermatologic Surgery and Oncology·W J Grabski, S J Salasche
Mar 1, 1985·The British Journal of Ophthalmology·A GarnerJ R Collin
Oct 1, 1984·American Journal of Surgery·H GoepfertM D Luna
May 1, 1984·Archives of Ophthalmology·J W GamelP Guibor
Dec 1, 1995·Journal of the American Academy of Dermatology·L M Cohen
Jul 1, 1995·Journal of the American Academy of Dermatology·R A Schwartz, D P Torre
Sep 1, 1993·Survey of Ophthalmology·C E Margo, K Waltz
Dec 1, 1993·American Journal of Clinical Pathology·H LaneP A Dervan
Feb 1, 1993·The British Journal of Ophthalmology·R J LeitchM A Parsons
Nov 1, 1995·Clinics in Dermatology·A C Markey
Feb 1, 1997·Journal of the American Academy of Dermatology·D J KarimipourL Lowe
Mar 31, 1997·American Journal of Medical Genetics·V E KimonisS J Bale
Jun 30, 1998·American Journal of Ophthalmology·K GündüzF Nathan
Apr 28, 1999·American Journal of Ophthalmology·M T CahillS M Kennedy
May 20, 1999·Human Pathology·T J Flotte, Martin C Mihm
Sep 8, 2001·Plastic and Reconstructive Surgery·D KrastinovaM B Kelly
Oct 18, 2001·Journal of Chemical Information and Computer Sciences·D BonchevA Dekmezian
Oct 20, 2001·Ophthalmic Plastic and Reconstructive Surgery·J A ShieldsRalph C Eagle
Jan 22, 2002·The American Journal of Dermatopathology·D HardissonF Contreras
Mar 19, 2002·Ophthalmic Plastic and Reconstructive Surgery·Bita EsmaeliVictor G Prieto
Sep 6, 2002·Clinical & Experimental Ophthalmology·Justin A Game, Rodger Davies
Feb 1, 2003·Survey of Ophthalmology·J A Shields, C L Shields
Mar 19, 2003·The British Journal of Ophthalmology·R M ConwayR M Conway
Feb 14, 2004·American Journal of Ophthalmology·Igor KaisermanJacob Pe'er
Mar 20, 2004·The British Journal of Dermatology·A M Hassanein, S M Glanz
May 7, 2004·The New England Journal of Medicine·Michael GirardiLynn D Wilson
Jul 22, 2004·Ophthalmic Plastic and Reconstructive Surgery·Brian G Brazzo, Norman Saffra
Oct 20, 2004·The Journal of Dermatology·Takaharu IkedaFukumi Furukawa
Oct 27, 2004·Cancer·William M MendenhallMark T Scarborough
Aug 23, 2005·Journal of the American Academy of Dermatology·Melissa A BogleMadeleine Duvic
Aug 23, 2005·The British Journal of Ophthalmology·Igal LeibovitchD Selva
Feb 1, 2006·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Bruce R Smoller
May 10, 2006·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Jeffrey K McKennaGlen M Bowen
Jun 17, 2006·Eye·K TumuluriB Leatherbarrow
Feb 7, 2007·Journal of Magnetic Resonance Imaging : JMRI·Franz J Wippold
Jun 15, 2007·Archives of Ophthalmology·Bibiana Jin ReiserJonathan W Kim
Nov 9, 2007·Acta Dermato-venereologica·Olivier OutteryckPatrick Vermersch
Jan 19, 2008·Science·Huichen FengPatrick S Moore
Mar 19, 2008·The American Journal of Surgical Pathology·Alistair RobsonEduardo Calonje
May 6, 2008·Ophthalmology·Nikolai Holak, Heinrich Holak
May 14, 2008·Archives of Ophthalmology·Ingrid BoldinAngelika Klein
May 27, 2008·Clinical Pediatrics·Laura D Briley, Charles M Phillips
Jul 22, 2008·Journal of the American Academy of Dermatology·Robert A SchwartzLaura Scuderi
Oct 8, 2008·The Journal of Dermatology·Ulker GülMurat Demiriz
Nov 5, 2008·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Carol BeadlingChristopher L Corless
Nov 20, 2008·The Journal of Dermatology·Tomoyasu HattoriOsamu Ishikawa
Dec 17, 2008·Dermatologic Therapy·Peggy B Liao
Dec 20, 2008·Clinics in Dermatology·C L Shields, J A Shields
Mar 24, 2009·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Mo-Lun ShenYu-Ming Wen
Mar 26, 2009·The American Journal of Dermatopathology·Brian S WaltherMarisa F Baldassano
Apr 23, 2009·The American Journal of Dermatopathology·Manuel Deprez, Sylvie Uffer
Oct 21, 2009·Orbit·Rajat Maheshwari, Sejal Maheshwari
Nov 18, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Charles M BalchVernon K Sondak
Dec 4, 2009·Applied Immunohistochemistry & Molecular Morphology : AIMM·Mahmoud Rezk A HusseinTaufik Dalati
Jan 27, 2010·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Abdel Kader El TalDavid A Mehregan
Jun 12, 2010·The Lancet Oncology·Robin J YoungPenella J Woll
Jun 15, 2010·Clinics in Dermatology·Christine J Ko
Jul 7, 2010·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Jae Ho JungHee Young Choi
Dec 21, 2010·Journal of the American Academy of Dermatology·Robert L FinneyJennie T Clarke
Jan 22, 2011·Diagnostic Cytopathology·Roberto Gabriel Albìn Cano, Juan Carlos Perez Cardenas
Feb 8, 2011·Southern Medical Journal·Hubert M Chodkiewicz, Philip R Cohen
Feb 12, 2011·Acta Dermato-venereologica·R Benjamin AldridgeJonathan L Rees
Jun 7, 2011·The New England Journal of Medicine·Paul B ChapmanBRIM-3 Study Group
Jul 23, 2011·The American Journal of Dermatopathology·Shin-ichi AnsaiTetsunori Kimura
Aug 25, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Thabo LappClaudia Auw-Hädrich
Sep 2, 2011·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Donald R DuerksenWilliam D Leslie
Nov 1, 2011·Journal français d'ophtalmologie·J Lasudry
Nov 1, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Frederick A JakobiecDaniel J Townsend
Feb 18, 2012·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Lixia Z EllisLeslie Stewart
Mar 31, 2012·The British Journal of Dermatology·P JayarajS Ghose
Apr 28, 2012·The Journal of Surgical Research·Michael C SoultRoger R Perry
May 4, 2012·Journal of the American Academy of Dermatology·Bonnie A LeeDongsi Lu
May 24, 2012·Ophthalmic Plastic and Reconstructive Surgery·Hee J KimHans Grossniklaus
Jun 8, 2012·The New England Journal of Medicine·Aleksandar SekulicAxel Hauschild
Jun 8, 2012·The New England Journal of Medicine·Jean Y TangErvin H Epstein
Jun 20, 2012·Archives of Dermatology·Sachiko OnoYumi Matsumura
Sep 25, 2012·The American Journal of Dermatopathology·Mara C WeinsteinKord Honda

Citations

Feb 28, 2015·Annales de dermatologie et de vénéréologie·E CinottiGroupe imagerie cutanée non invasive/ICNI de la SFD
Nov 30, 2016·International Ophthalmology Clinics·Viraj J MehtaRachel K Sobel

Related Concepts

Education, Medical, Continuing
Eyelid Neoplasms
Malignant Neoplasm of Skin
Biopsy
Malignant Neoplasms
Endocrine Gland Neoplasms
Epithelial Cells
Eye
Eyelid Structure
Neoplasm Metastasis

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