Malignancy after heart transplantation

Journal of the Chinese Medical Association : JCMA
Po-Lin ChenAn-Hang Yang

Abstract

The purpose of this study was to assess the incidence and type of malignancies after heart transplantation at a medical institute in Taiwan. From January 1987 to December 2008, a total of 66 patients who survived more than 30 days after transplantation were enrolled in this study. Of the 66 heart transplant recipients, 8 (12.1%) post-transplant malignancies were diagnosed: 5 posttransplant lymphoproliferative diseases (PTLD), 1 prostate cancer, 1 lung cancer, and 1 squamous cell carcinoma of the cheek. The clinical presentations were diverse, and the diagnoses were confirmed by biopsy. Only 1 patient died of PTLD and subsequent multiple organ failure. Cancer is a limiting factor for long-term survival after heart transplantation. The most common type in this study was PTLD. Early detection and aggressive treatment results in good response and preserves the allograft.

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Citations

Nov 30, 2012·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Tejaswi MudigondaSteven R Feldman
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Jan 22, 2015·Transplantation·Anake YoosabaiSuphamai Bunnapradist
Feb 5, 2011·American Journal of Clinical Oncology·Catherine Callaghan CoombsWilliam Barrett

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