Malignancy as a comorbidity in rheumatic diseases: a retrospective hospital-based study

Clinical Rheumatology
Hai-Long WangBao-Jin Hua

Abstract

Patients with Rheumatic diseases (RDs) are at an increased risk of malignancies compared with the general population. The aim of this study was to examine the relative frequency of several cancers in a single homogeneous cohort of patients with different RDs. Patients diagnosed with rheumatoid arthritis (RA), Ankylosing spondylitis (AS), Sjögren's syndrome (SS), systemic lupus erythematosus (SLE), systemic sclerosis (SSc), dermatomyositis (DM), or polymyositis were included. Out of 3982 adult residents admitted to the division of rheumatology, 61 malignancies were observed. The 2009 National Central Cancer Registry (NCCR) of China served as the reference for calculating standardized ratio (SR). The malignancy frequency had no difference between RDs with malignancy and the general population. Patients with SS and DM/PM showed an increased risk of non-Hodgkin's lymphoma (SR for SS patients = 9.709, 95% confidence interval (CI) = 4.602 to 17.916; SR for DM/PM = 35.714, 95% CI = 25.001 to 49.527). Patients with DM/PM and SSc showed an increased risk of lung cancer (SR for DM/PM = 10.638, 95% CI = 5.245 to 19.131; SR for SSc patients = 7.752, 95% CI = 3.295 to 15.309). Patients with SS and DM/PM showed an increased risk of ovary can...Continue Reading

References

Jul 30, 2005·Arthritis and Rheumatism·Soumya ChatterjeeMaureen D Mayes
Nov 17, 2005·Archives of Internal Medicine·Elias ZintzarasHaralampos M Moutsopoulos
Nov 23, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Karin Ekström SmedbyJohan Askling
Nov 6, 2007·Seminars in Arthritis and Rheumatism·Lydia AbásoloUNKNOWN EMECAR Study Group
Apr 25, 2008·Arthritis Research & Therapy·Allison L SmittenSamy Suissa
May 18, 2010·Rheumatology International·Toru YamadaHisashi Yamanaka
Nov 15, 2011·Autoimmunity Reviews·I MarieC Larroche
Jul 26, 2012·Rheumatology·Carl Turesson, Eric L Matteson
Nov 10, 2012·Rheumatic Diseases Clinics of North America·John J Cush, Kathryn H Dao
Mar 5, 2013·Chinese Journal of Cancer·Wanqing ChenJie He
Apr 12, 2013·Arthritis and Rheumatism·Akira OnishiAkio Morinobu
Mar 7, 2014·Journal of Clinical and Diagnostic Research : JCDR·Ananya PandaManisha Jana
Aug 29, 2014·Arthritis Research & Therapy·Sung Hae ChangEun Bong Lee
Nov 6, 2014·Arthritis & Rheumatology·Ami A ShahAntony Rosen
Dec 3, 2014·The Journal of Rheumatology·Zaixing YangRenqian Zhong
Aug 15, 2015·Arthritis Research & Therapy·Teresa A SimonSamy Suissa
Aug 19, 2016·Scientific Reports·Chuiwen DengFengchun Zhang
Nov 29, 2016·Rheumatic Diseases Clinics of North America·Raphaèle Seror, Xavier Mariette

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Citations

Sep 6, 2018·Expert Review of Clinical Immunology·Alexandra LadouceurAnn E Clarke
Feb 21, 2019·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jung Min BaeMiri Kim
Jul 13, 2019·International Journal of Rheumatic Diseases·Xin Rong LimUNKNOWN TTSH Rheumatoid Arthritis Study Group
Aug 26, 2020·International Journal of Rheumatic Diseases·Juyeon KangYoon-Kyoung Sung
May 1, 2018·Frontiers in Medicine·Alessia AlunnoFrancesco Carubbi
Mar 28, 2021·Joint, Bone, Spine : Revue Du Rhumatisme·Joanna KedraRaphaèle Seror
Sep 7, 2021·Frontiers in Immunology·Sreemol GokuladhasJustin O'Sullivan
May 2, 2018·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·S JayashreeDipita Bhakta-Guha
Mar 4, 2021·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Dylan HardenberghHoma Timlin

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