Malignancy associated with ovarian teratomas: frequency, histotypes, and diagnostic accuracy of intraoperative consultation

Annals of Diagnostic Pathology
Mohamed Mokhtar DesoukiAmal Kanbour-Shakir

Abstract

Mature cystic teratomas are common ovarian germ cell tumors that rarely undergo malignant transformation, and intraoperative consultation is generally not warranted. The aims of this study were to review a large number of ovarian teratomas (OTs), to document the rate and histotypes of associated malignancy, and to identify parameters that may be associated with malignancy. In this study, a retrospective medical record review of patients diagnosed as having OTs from 2002 to 2011 was performed. Patient age, tumor size, type, and laterality were obtained from pathology reports and operative notes. A total of 956 OTs that ranged in size from 0.3 to 45 cm were identified. Intraoperative consultation was requested in a total of 316 (33.1%) of 956. Intraoperative gross evaluation only was performed on 211 (66.8%) of 316, of which 4 cases were malignant on final diagnosis. Frozen section was performed on 105 (33.2%) of 316, of which 12 were malignant on final diagnosis. The final diagnoses of all OT cases were as follows: 26 (2.7%) of 956 were associated with malignant tumors. The latter were larger than benign cases (average sizes, 11.2 cm vs 6.5 cm; P < .001), and patients with malignant tumors were significantly older than those wit...Continue Reading

References

Aug 1, 1993·Archives of Surgery·M A SkinnerJ L Grosfeld
Aug 13, 2003·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·S TangjitgamolS Jesadapatarakul
Aug 11, 2004·Journal of Pediatric Endocrinology & Metabolism : JPEM·K S H de SilvaG L Warne
Aug 26, 2004·The Journal of Obstetrics and Gynaecology Research·Dittakarn Boriboonhirunsarn, Athita Sermboon
Apr 13, 2005·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·L R MedeirosM T Carballo
Feb 1, 2006·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·S-Y RimH-S Choi
Feb 2, 2008·Archives of Gynecology and Obstetrics·Keiko MekaruYoichi Aoki
Mar 25, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·An-Jen ChiangNelson N H Teng
Mar 26, 2011·Journal of Ovarian Research·Fatima A ZakkouriHassan Errihani

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Citations

Dec 10, 2016·The Journal of Obstetrics and Gynaecology Research·Hadas Ganer HermanShimon Ginath
Mar 30, 2016·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Roberto J VargasBryann S Bromley
Jul 13, 2017·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Shannon CoyMichelle S Hirsch
Oct 18, 2016·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Samuel G BorakWalter C Bell
Aug 3, 2021·Case Reports in Obstetrics and Gynecology·Mariam MahtateAziz Baydada

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