Malignancy in lung transplantation: biomarkers, gender differences, and consideration of a systems biology approach.

Transplantation
Sean M StuderNaftali Kaminski

Abstract

We present here new molecular tools such as gene expression microarrays as promising biomarkers for diagnosis and prognosis in lung cancer as well as for an early diagnosis of malignancy after lung transplantation. Data regarding gender differences in survival, recently collected in a single-institution study, may allow better targeting of immunosuppression goals to maintain effectiveness while minimizing cancer development and progression. Combining these differing types of data using an integrative approach that is the central theme of systems biology may allow us to provide powerful and more individualized risks of cancer after lung transplantation.

References

Mar 19, 2002·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Marc EstenneSamuel Yousem
Oct 31, 2003·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Jonathan B OrensUNKNOWN Pulmonary Council, International Society for Heart and Lung Transplantation
Jun 14, 2005·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Gavin J Gordon
Oct 8, 2005·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Jason D ChristieUNKNOWN ISHLT Working Group on Primary Lung Graft Dysfunction
May 30, 2006·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·UNKNOWN International Society of Heart and Lung Transplantation RegistryShaf Keshavjee
Aug 8, 2006·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Elbert P TrulockUNKNOWN International Society for Heart and Lung Transplantation
Aug 8, 2006·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Clément PicardMarc Stern
Jan 5, 2007·Proceedings of the American Thoracic Society·Sean M Studer, Naftali Kaminski

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Citations

May 27, 2014·The Annals of Thoracic Surgery·Anne B M OllandGilbert Massard

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