PMID: 9448616Feb 4, 1998Paper

Malignant change in the biliary tract after excision of choledochal cyst

The British Journal of Surgery
T IshibashiK Kanazawa

Abstract

Choledochal cyst is a rare congenital condition with a high risk of malignant change if untreated. The risk of malignancy after surgical excision of choledochal cyst is not known. Forty-eight patients with choledochal cysts managed over a 21-year period were reviewed, to determine the risk of malignant change after cyst excision. Thirty-nine of 48 patients had no carcinoma at first admission; their mean(s.d.) age was 20(18) years. Thirty-seven of 39 patients underwent cyst excision and cholecystectomy followed by hepaticoenterostomy. Cyst excision was incomplete in 28 of the 37 patients because dilated portions of the biliary ducts remained proximally and/or distally. In these 37 patients, no carcinoma has developed in the remnant proximal hepatic duct or the terminal bile duct after mean(s.d.) follow-up of 9.1(6.4) years. In the remaining nine patients, biliary carcinoma was diagnosed at the first visit. Six patients died from recurrence with a mean(s.d.) survival time of 13(11) months, while three patients were alive and free from recurrence 2 months, 1 year and 7 years after operation. Malignant change has not been observed after total or subtotal excision of choledochal cysts in this series.

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Citations

Oct 1, 2005·Pediatric Surgery International·Tsugumichi KoshinagaRyouichi Tomita
Aug 5, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Ming-Shian TsaiWei-Jao Chen
Apr 7, 2010·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Hans Joachim KirschnerJoerg Fuchs
Feb 6, 2007·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Hasan M H AbbasBasil J Ammori
Oct 1, 2010·Annals of Surgery·Kathryn M ZieglerJay L Grosfeld
Sep 20, 2012·Journal of Gastroenterology and Hepatology·Taku OhashiYoichi Ajioka
Dec 26, 2006·Annals of Surgical Oncology·Kjetil Søreide, Jon Arne Søreide
Dec 23, 2009·World Journal of Gastroenterology : WJG·Masato WatanabeYasuyuki Sugiyama
Mar 2, 2011·World Journal of Surgery·Min-Jeong ChoSung-Gyu Lee
Feb 25, 2014·Surgical Oncology Clinics of North America·Mathew M Augustine, Yuman Fong
Feb 3, 2009·Journal of the American College of Surgeons·Chinnusamy PalaniveluPalanisamy Senthilnathan
Feb 27, 2018·The British Journal of Surgery·A Ten HoveR H J de Kleine
Nov 19, 2004·The British Journal of Surgery·K SöreideJ A Söreide
Mar 28, 2020·Clinics·Ana Cristina Aoun TannuriUenis Tannuri

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