PMID: 6989478Apr 1, 1980Paper

Malignant effusions in recurrent breast cancer: steroid hormone receptor analysis of effusion fluid derived cells

K S McCartyK S McCarty


Estrogen and progesterone receptor determination in breast cancer is of significance in determining a patient's potential response to hormonal manipulation. One practical limitation to this procedure has been availability of material for receptor assay. We describe 12 patients in whom quantitative estrogen and/or progesterone receptor analysis was accomplished utilizing tumor cells obtained from malignant effusions. The ability to obtain quantitative steroid receptor data on material derived from malignant effusions provides an effective source for this important biochemical parameter in patients in whom no other tumor tissue is available for study.


Aug 1, 1978·American Journal of Clinical Pathology·S H Lee
Jul 12, 1976·Biochemical and Biophysical Research Communications·J T Woosley, T G Muldoon
Jan 1, 1978·Annals of Internal Medicine·S S LeghaF M Muggia
Jul 4, 1977·JAMA : the Journal of the American Medical Association·D T Kiang, B J Kennedy
Oct 26, 1978·The New England Journal of Medicine·M E Lippman, J C Allegra
Jan 1, 1977·Annals of Internal Medicine·C M HaskellS G Korenman
Apr 1, 1976·Annals of Internal Medicine·G P CanellosR C Young

Related Concepts

Mammary Neoplasms, Human
Centrifugation, Density Gradient
Exudates and Transudates
Immunofluorescence Assay
Neoplasm Recurrence, Local
Estrogen Nuclear Receptor
Receptors, Progesterone

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