Malignant epithelioid renal angiomyolipoma involving the inferior vena cava in a patient with tuberous sclerosis

Urologia Internationalis
S M MoudouniP Thibault

Abstract

Renal angiomyolipomas (AMLs) are mesenchymal tumors that occur either sporadically or are associated with tuberous sclerosis, and are generally considered to be benign. Malignant AML is extremely rare, and most are found to be epithelioid histopathologically. The authors report the case of a patient followed for renal AML. On CT surveillance, this lesion developed features of a malignant tumor involving the renal vein and inferior vena cava. The patient was treated by nephrectomy and tumor thrombectomy with retroperitoneal lymph node dissection. Histological examination demonstrated renal AML with a malignant epithelioid contingent. The various aspects of this histological and radiological variant are discussed.

References

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Citations

Apr 30, 2014·Case Reports in Urology·Adrien RiviereJean-Jacques Patard
Mar 1, 2011·The Kaohsiung Journal of Medical Sciences·Deyi LuoQiang Dong
Jul 7, 2015·Annals of Diagnostic Pathology·Khin Thway, Cyril Fisher
Mar 26, 2015·Seminars in Diagnostic Pathology·Guido MartignoniFranco Bonetti
Dec 17, 2020·Journal of Clinical Ultrasound : JCU·Dan WangMingxing Xie

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