Malignant glomus tumour of larynx: first case report and literature review

The Journal of Laryngology and Otology
N AslamR U Khan

Abstract

We describe the first reported case of a malignant glomus tumour of the larynx. Case report and review of the world literature concerning malignant glomus tumours. A 37-year-old man presented with progressive hoarseness and dyspnoea. A smooth, right-sided laryngeal mass was found on flexible nasolaryngoscopy. Initial biopsy of this lesion was reported as a true 'glomus tumour', which is a benign lesion. Wide local excision was performed. The final histology of this specimen showed it to be a 'malignant glomus tumour'. Immunohistochemistry was positive for smooth muscle actin, collagen type IV, vimentin and cluster of differentiation 34 glycoprotein. Total laryngectomy was then performed as a definitive curative procedure. Glomus tumour is rarely found in visceral locations. This tumour and its malignant counterpart are rare differential diagnoses of laryngeal masses.

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Citations

Aug 4, 2015·Case Reports in Surgery·Kemal BeksaçCihangir Ozaslan
Jan 26, 2016·Annals of Plastic Surgery·Tingmao ChouChien Liang Ho
Jul 13, 2017·Case Reports in Pathology·Ammar AlmaghrabiHaneen Al-Maghrabi
Nov 5, 2013·Case Reports in Vascular Medicine·Jan HrubýJaroslav Lindner

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