PMID: 22576571May 12, 2012Paper

Malignant lymphoma presenting as inflammation of unknown origin

Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology
Hiroyuki YamashitaAkio Mimori

Abstract

We classified underlying diseases presenting as inflammation of unknown origin in division of rheumatic diseases. On the other hand, patients with malignant lymphoma (ML) varying in cause and symptoms are often admitted to our Rheumatology Division as cases of malignant disease presenting with fever of unknown origin. Clinical records over 5 years were reviewed for 246 cases of undiagnosed inflammatory diseases at hospitalization. The 246 patients included 76 patients with infection, 116 with rheumatic disease, 8 with solid cancer, 9 with drug-induced fever, 10 with other disorders, and 27 with suspected ML. Of theses, malignant lymphoma (ML) was diagnosed in 20 patients (5 Mature T-cell and NK-cell neoplasms, 3 Hodgkin lymphomas, and 12 Mature B cell neoplasms including 5 Intravascular large B-cell lymphoma (IVLBCL)). The reasons for hospitalization were underlying collagen disease in 6 patients, medical workup for fever of unknown origin in 8 patients, and symptoms suggestive of collagen disease in 6. Nearly all of these patients presented with fever and other B symptoms, frequently with concurrent hypoxemia and hemophagocytic syndrome in IVLBCL. For diagnostic purposes, biopsy sites were determined by 18 fluorodexyglucose-po...Continue Reading

References

Jun 1, 1969·Biulleten' eksperimental'noĭ biologii i meditsiny·I A Oĭvin, L V Koroleva
Jan 25, 2003·The American Journal of Medicine·Sharlene GillClifford ChanYan
Dec 13, 2007·Respiration; International Review of Thoracic Diseases·Tevfik OzluSavas Ozsu
Oct 20, 2010·Annals of Hematology·Kosei MatsueMasami Takeuchi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Biology: Molecular Imaging

Molecular imaging enables noninvasive imaging of key molecules that are crucial to tumor biology. Discover the latest research in molecular imaging in cancer biology in this feed.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.

Related Papers

Journal des sciences médicales de Lille
G VINCENT
Transactions of the Medical Society of London
F D Hart
Revue Du Rhumatisme : Joint, Bone, Spine Diseases
T N An, N V Ngoc
© 2021 Meta ULC. All rights reserved