Malignant melanoma: advances in diagnosis, prognosis, and treatment

Seminars in Cutaneous Medicine and Surgery
Michael Krathen

Abstract

The detection of cutaneous melanoma still largely relies on clinical suspicion, skin biopsy, and histopathologic evaluation. New technologies are being evaluated to bypass the skin biopsy in the detection of melanoma. The quest for reliable biomarkers, with respect to subclinical detection, prognosis, and predicting treatment response, is longstanding and ongoing. New therapies have been developed for metastatic disease, including targeted small molecule inhibitors as well as immune modulators.

References

Jan 1, 1994·The British Journal of Dermatology·M F HealsmithR A Graham-Brown
Sep 12, 2000·The American Journal of Pathology·B C BastianD Pinkel
May 28, 2004·Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B·Jeff D HarvellMatt van de Rijn
Jun 16, 2004·CA: a Cancer Journal for Clinicians·Charles M BalchJohn F Thompson
Dec 9, 2004·JAMA : the Journal of the American Medical Association·Naheed R AbbasiDavid Polsky
Apr 20, 2005·Archives of Dermatology·Julie GachonJean Jacques Grob
Aug 18, 2005·Journal of the National Cancer Institute·Lisa M McShaneUNKNOWN Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics
Dec 25, 2008·Nature Clinical Practice. Oncology·Allison R LarsonRhoda M Alani
Jul 28, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·H GogasR Dummer
Oct 23, 2009·The Journal of Investigative Dermatology·Maria C Garrido, Boris C Bastian
Nov 18, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Charles M BalchVernon K Sondak
Jun 8, 2010·The New England Journal of Medicine·F Stephen HodiWalter J Urba
Jul 14, 2010·Journal of the American Academy of Dermatology·Holly C Engasser, Erin M Warshaw
Dec 7, 2010·Archives of Pathology & Laboratory Medicine·Phyllis A Gimotty, DuPont Guerry
Jan 26, 2011·The American Journal of Surgical Pathology·Leon RaskinDouglas R Fullen
Feb 8, 2011·The British Journal of Dermatology·W WachsmanS Chang
Mar 11, 2011·The Journal of Investigative Dermatology·Clara Curiel-LewandrowskiRobert S Stern
Mar 25, 2011·Journal of the American Academy of Dermatology·Vincenzo PanasitiPaola Londei
Jun 7, 2011·The New England Journal of Medicine·Paul B ChapmanUNKNOWN BRIM-3 Study Group
Jun 7, 2011·The New England Journal of Medicine·Caroline RobertJedd D Wolchok
Jun 7, 2011·JAMA : the Journal of the American Medical Association·Richard D CarvajalGary K Schwartz
Aug 16, 2011·Clinica Chimica Acta; International Journal of Clinical Chemistry·Pamela PinzaniClaudio Orlando
Aug 16, 2011·Human Pathology·Erica C RushingRhoda M Alani

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Citations

May 28, 2016·Seminars in Diagnostic Pathology·Mark R Wick
Jun 8, 2017·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Yi YangChengxin Li

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