PMID: 8467454May 1, 1993Paper

Malignant melanoma in different ethnic groups in Israel. Incidence and biologic behavior

Cancer
M GutmanS Chaitchik

Abstract

The Jewish population of Israel is divided into two ethnic groups: Ashkenazic Jews (AJ) who immigrated from Europe and are fair-skinned, and Sephardic Jews (SJ) who immigrated from the Orient and Africa and who are dark-skinned. The biologic behavior of malignant melanoma (MM) in these two groups has not been investigated. Three hundred forty-eight of 380 patients with MM, who could be accurately grouped ethnically, constitute this study group. The gender, site and depth of primary tumor, metastatic involvement and survival analysis, including univariate analysis for level of invasion, were examined. Of 348 patients with MM, 285 were AJ and 63 were SJ. The female:male ratio was 2:1 and 0.9:1, for AJ and SJ, respectively (P < 0.05). Lesion site distribution was similar. The lesions were more invasive in SJ, 53% Clark level 4-5 versus 41% in AJ (P < 0.05). The 5-year survival was worse in SJ relative to AJ--50% versus 71% for female patients and 30% versus 62% for male patients--but did not reach statistical significance (NS). The actuarial 10-year survival showed poorer survival for female SJ: 27% versus 67% in female AJ (P < 0.05) and male SJ; 32% versus 65% in male AJ (P < 0.01). For all stage I MM, the actuarial 10-year survi...Continue Reading

References

May 1, 1978·Cancer·L TeppoT Hakulinsen
Mar 1, 1975·Cancer·I D FlemingJ S Rankin
May 1, 1976·Annals of Surgery·E T KrementzR F Ryan
Aug 15, 1990·International Journal of Cancer. Journal International Du Cancer·M McCredieJ M Ford
Aug 26, 1989·Lancet·R M MacKieT C Aitchison
Aug 22, 1987·Lancet·R R Jones
Sep 15, 1988·International Journal of Cancer. Journal International Du Cancer·A OsterlindO M Jensen
Sep 1, 1973·Journal of the National Cancer Institute·M Movshovitz, B Modan
Oct 31, 1970·The Medical Journal of Australia·J A Lee, J M Merrill
May 15, 1966·International Journal of Cancer. Journal International Du Cancer·K T Abou-Daoud
Oct 1, 1981·Journal of the American Academy of Dermatology·A N Houghton, M V Viola
Dec 15, 1980·International Journal of Cancer. Journal International Du Cancer·C D HolmanB K Armstrong
Feb 15, 1980·Cancer·M W Hinds, L N Kolonel
May 1, 1980·British Journal of Cancer·J A Lee, D Strickland
Mar 1, 1965·The Journal of Laryngology and Otology·C S MUIR

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Citations

Nov 2, 2004·Familial Cancer·Henry T LynchGershon Y Locker
Aug 12, 1998·Clinics in Dermatology·S BrennerM Landau
Mar 1, 1996·European Journal of Cancer Care·J Timpson
Nov 7, 1998·Clinical Chemistry and Laboratory Medicine : CCLM·E A YakobsonH Peretz
Apr 17, 2008·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Marie NorredamNiels Keiding
Jan 25, 2006·Melanoma Research·Tal FriedmanYosefa Bar Dayan

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