PMID: 6112537May 30, 1981Paper

Malignant melanoma in renal-transplant recipients

Lancet
M H GreeneW H Clark

Abstract

14 patients who developed cutaneous malignant melanoma (CMM) after renal transplantation were studied. Histological review of the primary melanomas revealed that all 10 evaluable patients had a precursor naevus from which the CMM arose, 7 of which were dysplastic, and that 13 of the 14 patients had an abnormal host response to the tumour, characterised by absence of the usual lymphocyte/ macrophage infiltrate. These observations suggest that CMM in renal-transplant recipients evolves from precursor naevi in immunosuppressed patients who are unable to mount an appropriate cellular immune response to neoplastic cells. The clinical detection of dysplastic naevi offers an opportunity to identify in advance those immunosuppressed patients who are prone to melanoma and to modify their medical management accordingly.

References

May 1, 1971·Cancer·D C WallaceG R McLeod
Jan 1, 1969·Archives of Dermatology·G A GellinL Garfinkel
May 1, 1980·Transplantation·E K SpeesL E Zimmerman
Sep 1, 1980·International Journal of Dermatology·J C Bystryn
Jun 14, 1980·British Medical Journal·L J KinlenA J Wing

❮ Previous
Next ❯

Citations

Mar 17, 2010·Archives of Dermatology·Porcia T BradfordMargaret A Tucker
Feb 27, 2001·European Journal of Radiology·J MoppettA W Duncan
Jun 12, 2001·European Journal of Radiology·J MoppettA W Duncan
May 1, 1997·Clinics in Dermatology·J N Bouwes Bavinck, R J Berkhout
Jun 26, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E VaccherU Tirelli
Jul 25, 2000·The British Journal of Dermatology·D B McKennaJ A Hunter
Sep 4, 1999·Neuropathology and Applied Neurobiology·A KingP Barnes
Jul 5, 2001·Pediatric Dermatology·N B SilverbergT A Laude
Jan 10, 1985·The New England Journal of Medicine·M H GreeneM C Fraser
Mar 27, 1997·The New England Journal of Medicine·R E CurtisJ D Boice
May 6, 2004·Journal of the National Cancer Institute·Henrik Toft SørensenMargaret R Karagas
Nov 11, 1999·Current Opinion in Pediatrics·M T Hoang, S F Friedlander
Aug 1, 1990·The British Journal of Dermatology·Y MérotE Frenk
May 1, 1992·The British Journal of Dermatology·J M McGregorC Darley
Mar 1, 1991·Clinical and Experimental Dermatology·J M McGregorD M MacDonald
Jan 1, 1993·Clinical and Experimental Dermatology·B R Hughes, J A Cotterill
Apr 1, 1991·International Journal of Dermatology·I BetllochA Vilar
Jan 1, 1992·International Journal of Dermatology·I L RothmanM V Klaus
Jul 1, 1994·International Journal of Dermatology·P F RockleyS K Tyring
Mar 1, 1996·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·H M Gloster, D G Brodland
Jan 27, 2010·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Jerry D BrewerAmy L Weaver
Apr 28, 2007·Pediatric Dermatology·Jason C ReutterPamela A Groben
Apr 22, 2005·Dermatologic Therapy·Jennifer Baron, Alfons Krol
Jul 8, 1989·BMJ : British Medical Journal·B R HughesC C Bailey
Dec 12, 2012·Journal of Skin Cancer·Faisal R Ali, John T Lear
Dec 22, 2012·Case Reports in Transplantation·Kathryn T ChenJeffrey M Farma
Nov 24, 2007·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·I Kuijken, J N Bavinck
Jun 6, 2009·American Journal of Clinical Dermatology·Guillermo VillalónEsperanza Jordá
Nov 7, 2012·Indian Dermatology Online Journal·Giuseppe Noto
Jul 22, 1995·Lancet·J J Goedert, T R Coté
Sep 21, 2004·The British Journal of Dermatology·S Fukushima, N Hatta
Oct 25, 2007·The Australasian Journal of Dermatology·Quan Q Dinh, Alvin H Chong
Feb 1, 2006·The British Journal of Dermatology·L Le MireF Wojnarowska
Aug 5, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Clara J K LamLindsay M Morton
Apr 21, 2004·Journal of the American Academy of Dermatology·Alun V EvansRobin Russell-Jones
Nov 23, 2006·Current Problems in Surgery·Cecelia E SchmalbachCarol R Bradford
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Lester J Fahrner
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Christopher HarrisRemy H Blanchaert
Jan 1, 1984·Medical Decision Making : an International Journal of the Society for Medical Decision Making·G J CuchuralS G Pauker
Apr 30, 2005·The International Journal of Lower Extremity Wounds·A RekhaA Shivanraj
Sep 25, 1999·International Journal of Cancer. Journal International Du Cancer·C WassbergU Ringborg
Jan 27, 1996·Transplantation·I Penn

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The British Journal of Dermatology
L Le MireF T Wojnarowska
Clinical and Experimental Dermatology
J N Barker, D M MacDonald
Journal of the American Academy of Dermatology
C H SmithD M MacDonald
© 2021 Meta ULC. All rights reserved