Malignant melanoma of the vagina: pejorative location

Gynécologie, obstétrique & fertilité
T GauthierP Morice

Abstract

The aim of this study was to describe the clinical features of vaginal melanoma and treatments available. This is a retrospective review of patients with primary vaginal melanoma operated from 2000 to 2010 at Gustave-Roussy Institute. Six patients had surgery for a vaginal melanoma out of 37 patients operated for vaginal cancer in our institute in the same period (13.6%). Median age was 53.5 years [48-66]. The melanoma presented as a macroscopically visible nodular tumor in all case. Median tumour size was 5.4cm [1.5-15]. Five of the six patients had a [18F] fluoro-deoxy-glucose positron-emission tomography combined with integrated computed tomography (FDG-PET/CT) before surgery. Initial management included two conservative treatments and four colpectomy with one anterior exenteration. Two sigmoidcolpoplasties were performed. Lymph node metastases were found in only one patient. Median progression free survival was 10.5 months [4-51]. All patients have relapsed, three of them in the 6 months following surgery. Recurrences were local in three patients and distant in three patients. Local recurrences were surgically treated. In one case, electrochemotherapy was performed. One patient with locoregional disease underwent a pelvic i...Continue Reading

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Citations

Jan 1, 2013·The Pan African Medical Journal·Amal BennaniAffaf Amarti
Mar 5, 2016·The American Journal of Hospice & Palliative Care·Marco CascellaArturo Cuomo
Jan 31, 2016·Melanoma Research·Yukiharu TodoHidenori Kato
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Feb 17, 2021·Journal of Gynecology Obstetrics and Human Reproduction·Marine JosteJean Leveque

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