Mar 17, 2020

Malignant mesothelioma following repeated exposures to cosmetic talc: A case series of 75 patients

American Journal of Industrial Medicine
Theresa S EmoryRichard L Kradin

Abstract

Asbestos is the primary known cause of malignant mesothelioma. Some cosmetic talc products have been shown to contain asbestos. Recently, repeated exposures to cosmetic talc have been implicated as a cause of mesothelioma. Seventy-five individuals (64 females; 11 males) with malignant mesothelioma, whose only known exposure to asbestos was repeated exposures to cosmetic talcum powders, were reviewed in medical-legal consultation. Out of the 75 cases, 11 were examined for asbestiform fibers. All subjects had pathologically confirmed malignant mesothelioma. The mean age at diagnosis was 61 ± 17 years. The mean latency from exposure to diagnosis was 50 ± 13 years. The mean exposure duration was 33 ± 16 years. Four mesotheliomas (5%) occurred in individuals working as barbers/cosmetologists, or in a family member who swept the barber shop. Twelve (16%) occurred in individuals less than 45 years old (10 females; 2 males). Forty-eight mesotheliomas were pleural (40 females; 8 males), 23 were peritoneal (21 females; 2 males). Two presented with concomitant pleural and peritoneal disease. There was one pericardial, and one testicular mesothelioma. The majority (51) were of the epithelioid histological subtype, followed by 13 biphasic, ...Continue Reading

  • References14
  • Citations2

References

  • References14
  • Citations2

Mentioned in this Paper

Mesothelioma
Peritoneal
Malignant Mesothelioma
Tremolite Asbestos
Peritoneal Diseases
Barber-hairdresser
Subtype (Attribute)
Anthophyllite
Talc
Fiber

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