PMID: 7538149Feb 1, 1995Paper

Malignant myoepithelioma (myoepithelial carcinoma) of the breast: a detailed cytokeratin study

Journal of Clinical Pathology
S R LakhaniJ P Sloane

Abstract

To study the expression of a range of cytokeratins by malignant myoepithelioma of the breast. Immunophenotyping was carried out using a panel of antibodies on paraffin wax embedded and frozen material using immunohistochemistry and double-labelled immunofluorescence. Electron microscopy was also performed. The tumour cells were positive for CAM 5.2, actin, vimentin, and cytokeratin 14 and negative for cytokeratins 18 and 19. Electron microscopy showed well formed desmosomes and hemidesmosomes together with pinocytic vesicles, plentiful rough endoplasmic reticulum and 6 nM microfilaments with focal densities. The pattern of cytokeratin expression provides further evidence that tumours with a specific myoepithelial phenotype occur rarely in the breast.

References

Nov 1, 1992·The American Journal of Surgical Pathology·M Tamai
Jun 1, 1991·The American Journal of Surgical Pathology·F A Tavassoli
Dec 1, 1982·The American Journal of Surgical Pathology·R A Erlandson, P P Rosen

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Citations

Mar 11, 2008·Breast Cancer Research and Treatment·Emad A RakhaIan O Ellis
Jun 30, 2006·Journal of Mammary Gland Biology and Neoplasia·Catherine ClarkeSunil R Lakhani
Apr 6, 2004·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·K A BehranwalaG P H Gui
Apr 6, 2013·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Werner BoeckerIgor Buchwalow
Feb 27, 2001·The American Journal of Surgical Pathology·R E JimenezD W Visscher
Oct 15, 2005·The American Journal of Surgical Pathology·William G DavisMichael Z Gilcrease
Jul 2, 2003·Journal of Clinical Pathology·M Pia-FoschiniS R Lakhani
Feb 2, 2013·Rare Tumors·Brijesh ThakurSmita Chauhan
Aug 29, 2013·Case Reports in Oncological Medicine·Yumi EndoTatsuya Toyama
Dec 26, 2003·Seminars in Diagnostic Pathology·Audrey K BennettMark R Wick
May 26, 2016·Virchows Archiv : an International Journal of Pathology·Fabian LeoHans Kreipe
Apr 10, 2004·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Rachel Kesse-Adu, Sami Shousha
Jun 26, 1999·Histopathology·P HinzeD Katenkamp
Jul 27, 2010·Virchows Archiv : an International Journal of Pathology·Natalia BuzaFattaneh A Tavassoli
Apr 29, 2016·Molecular and Clinical Oncology·Maria PapazianNikolaos Ziras
Mar 16, 2001·Breast Cancer Research : BCR·S R Lakhani, M J O'Hare
Jul 6, 2000·Laboratory Investigation; a Journal of Technical Methods and Pathology·C JonesS R Lakhani
Dec 20, 2007·Applied Immunohistochemistry & Molecular Morphology : AIMM·Min En NgaNorman Walford

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