PMID: 9656117Jul 10, 1998Paper

Malignant schwannoma of the uterine cervix: a study of three cases

International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists
S B KeelR H Young

Abstract

Pure sarcomas of the uterine cervix are rare; most of those reported have been leiomyosarcomas or rhabdomyosarcomas. Minimal data exists on malignant nerve sheath tumors in this site; only one typical example and one melanocytic example have been reported. We report three additional examples here in three patients 25, 65, and 73 years of age. The two older patients had vaginal bleeding and underwent hysterectomy as initial treatment. The youngest patient initially underwent only polypectomy. The tumors were 1.3, 4.4, and 5.0 cm in greatest dimension. The tumors were red-grey to white: two were polypoid and the third was ulcerated. The dominant microscopic appearance was that of cellular fascicles of spindle cells with hyperchromatic nuclei and eosinophilic cytoplasm. However, hypocellular areas were striking in each case; the hypocellular areas were fibromatous in two tumors and two had areas with a myxoid stroma (prominent in one). One tumor focally had cellular aggregates with a swirling pattern within a hypocellular background. Epithelioid foci in which tumor cells were rounded with conspicuous eosinophilic cytoplasm were focally prominent in one case. Mitoses were readily identified in each case. All three tumors were posit...Continue Reading

Citations

Nov 30, 2006·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Z GaoA E Anderson
Sep 20, 2006·Diagnostic Pathology·Oluwole Fadare
Jan 16, 2013·Case Reports in Pathology·Maryam TahmasbiArdeshir Hakam
Apr 11, 2001·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·G P Nielsen, R H Young
Feb 24, 2018·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Valentina SangiorgioEnzo Ricciardi
Feb 4, 2009·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Emanuela VerasRussell Vang
Dec 23, 2009·The Journal of Obstetrics and Gynaecology Research·Na Rae KimSeung Yeon Ha
Nov 19, 2010·The American Journal of Surgical Pathology·Laurence de LevalEsther Oliva
Sep 15, 2005·The American Journal of Surgical Pathology·Patricia M BakerEsther Oliva
Mar 29, 2019·Obstetrics & Gynecology Science·Biswajit DeyVandana Raphael
Sep 26, 2003·Pathology International·Satomi KasashimaYoshio Oda
Sep 22, 2007·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Gustavo R de A FocchiJaime Prat
Apr 9, 2015·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Kristin C ShawPaul N Staats
Dec 1, 2009·Surgical Pathology Clinics·Koen K Van de Vijver, Esther Oliva

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