Malignant spinal cord compression: NICE guidance, improvements and challenges

QJM : Monthly Journal of the Association of Physicians
P SavageC Ulbricht

Abstract

Malignant spinal cord compression (mSCC) is one of the most serious complications of cancer. Recent NICE guidance has aimed to improve patient pathways and outcomes for patients with mSCC. We have examined the current presentations, management and outcomes for patients with mSCC in West London following the implementation of the NICE guidance. The electronic records and clinical notes were reviewed for all patients assessed for confirmed or potential mSCC at Charing Cross Hospital in 2012. Details on the number of referrals, the proportion with confirmed mSCC, the cancer diagnosis, treatment and outcome were analysed. 191 patients were reviewed with 127 (66%) cases of confirmed mSCC. The commonest tumour types were prostate cancer (26 cases), lung cancer (26), breast cancer (21) and kidney cancer (15). 21% of the patients had no previous cancer diagnosis; mSCC was their presenting diagnostic event. Radiotherapy was the predominant management, 24% of the patients had first line surgical treatment. At presentation 62% of patients were either chair or bed bound. Treatment brought important mobility benefits to all patients groups with 20% of the initially chair or bed bound patients leaving the hospital with independent mobility. ...Continue Reading

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Citations

Mar 24, 2016·Therapeutic Advances in Neurological Disorders·Lukas GrassnerJohann Sellner
Apr 8, 2017·Mayo Clinic Proceedings·Thorvardur R HalfdanarsonBo E Madsen
Jul 12, 2018·British Journal of Hospital Medicine·Romy Ni ChleirighCatherine C Mitchell
Oct 8, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Olga LaurBharti Khurana
Jan 26, 2021·Global Spine Journal·Sepehr KhosraviVafa Rahimi-Movaghar
Dec 21, 2018·Emerging Topics in Life Sciences·Alain VellaArmando Del Río Hernández
Dec 11, 2020·Neuro-oncology Practice·Jared S FridleyZiya L Gokaslan
Feb 19, 2021·Global Spine Journal·Floris R van TolJorrit-J Verlaan
May 17, 2021·The Spine Journal : Official Journal of the North American Spine Society·Lananh NguyenAndrew J Schoenfeld
Aug 27, 2021·Frontiers in Neurology·Leonie Müller-JensenWolf Ulrich Schmidt

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